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  1. Replies
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    Lean body mass loss is absolutely necessary and...

    Lean body mass loss is absolutely necessary and expected in order to accommodate your actual weight. Take a look at any individual that is approaching morbid obesity and you will be absolutely...
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    The real takeaway from this study is ... whenever...

    The real takeaway from this study is ... whenever you see the celeb flavour of the day touting how they lost 2 lbs. a day for a week on the cover of some woman's magazine ( the men's magazines tend...
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    I don't think that there is much credibility to...

    I don't think that there is much credibility to the post workout eating window, which means that there is no need to actually have a meal within that 1 - 2 hours following your workout. With that...
  4. The basic problem with cholesterol numbers is due...

    The basic problem with cholesterol numbers is due to the fact that the bulk of the cholesterol being reported comes from endogenous rather than exogenous sources. That is, the cholesterol numbers...
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    Et voila! ...

    Et voila!

    -PK
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    Here's a really interesting paper that has more...

    Here's a really interesting paper that has more to say along these lines:



    The paper is definitely worth a read, it is really interesting, but here are some key points, as I see them:



    ...
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    I'm not an advocate of an eating window, but I do...

    I'm not an advocate of an eating window, but I do advocate eating a single meal a day. Further, I also think there is a lot of merit in eating that meal at a consistent time for a number of reasons....
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    Hi Dan, My position on BCAAs hasn't really...

    Hi Dan,

    My position on BCAAs hasn't really changed. They look interesting, and at worst, I think they are merely benign. I haven't really undertaken to consistently use BCAAs to determine what...
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    Leptin mediates food intake by interacting with...

    Leptin mediates food intake by interacting with specific brain centers that control appetite. In particular, this means the hypothalamus. The hypothalamus is sensitive to a variety of factors,...
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    Well, it's a literature review, so, there's not a...

    Well, it's a literature review, so, there's not a lot to critique. Apart from that, it's a collection of literature, which is great since it gives one a lot of reading to do with fairly low effort. ...
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    One meal a day, and I skip that one meal once a...

    One meal a day, and I skip that one meal once a week which makes for a weekly 36 or so hour fast.

    -PK
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    When I started doing this, I basically ate...

    When I started doing this, I basically ate roughly whatever I felt like eating, and I was still losing weight. Things seemed to accelerate once I started to pay closer attention to what I was...
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    Yes. I generally try no to get buried in...

    Yes. I generally try no to get buried in acronymitis and give the actual full term before using the acronym, but that one got by me.

    -PK
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    I basically agree with your premises, but that...

    I basically agree with your premises, but that study you linked is absolutely awful ...

    First, it is from 1973, and while age should not be taken to be a detractor in a knee-jerk fashion, surely...
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    Quite the opposite, actually. I'm arguing that...

    Quite the opposite, actually. I'm arguing that it would be metabolically insane to be unable to assimilate the most energy dense substrate, with or without insulin. Eating a high calorie high fat...
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    It's about time that we introduced you to...

    It's about time that we introduced you to something called acylation stimulating protein, or ASP. If you think that the acyl bit sounds vaguely familiar, then you may have seen it in reference to...
  17. Nothing against you, Neckhammer, but I'm...

    Nothing against you, Neckhammer, but I'm skeptical of Peter Attia, especially considering that his website used to be called "waroninsulin.com", and you can still access it via that DNS entry. It...
  18. The distinction you wish to make is between...

    The distinction you wish to make is between pathological and physiological insulin resistance. A pathology is a disease, whereas anything deemed physiological means that it is within the normal...
  19. You are fighting a losing battle against osmosis....

    You are fighting a losing battle against osmosis. Stored glycogen is water soluble, which means as you increase the glycogen content of a cell, you must necessarily increase the amount of water in...
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    Your profile doesn't specify your gender, so I'm...

    Your profile doesn't specify your gender, so I'm wondering if by any chance you are female?

    Just anecdotally, it seems that women are more prone to this. I've put up a quick four question...
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    I'm certainly still at it... -PK

    I'm certainly still at it...

    -PK
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    If you have spent any amount of time in a...

    If you have spent any amount of time in a commercial building, then you are undoubtedly very familiar with emergency lighting devices, as they are ubiquitous, given that their presence is mandated by...
  23. Thread: Protein

    by pklopp
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    Why do you believe this source to be...

    Why do you believe this source to be authoritative?

    -PK
  24. Thread: Protein

    by pklopp
    Replies
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    6,480

    I'm not sure of the source of your protein...

    I'm not sure of the source of your protein requirements assumptions. To the best of my knowledge, the recommended intake for athletes is in the range of 1.3 to 1.5g per kg of bodyweight. The RDA is...
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    For those who want the Cahill study without...

    For those who want the Cahill study without needing to pay anything:

    http://www.med.upenn.edu/timm/documents/ReviewArticleTIMM2008-9Lazar-1.pdf

    -PK
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