Is Stephan Guyenet suggesting Gary Taubes is wrong re insulin resistance?
[QUOTE]High circulating insulin is probably an adaptive response to insulin resistance in the body, which develops as fat cells enlarge and become less effective at trapping fatty acids and keeping them where they should be (there may also be a contribution from inflammation that may or may not be independent of the changes in fatty acid handling). Elevated insulin is probably the body's way of trying to compensate for this defect and keep fat in fat cells, but it does not fully compensate for the insulin resistance in fat tissue that progressively develops as fat cells enlarge. Evelyn Kocur has written about this quite a bit. This defect can be largely reversed by fat loss, as demonstrated by the fact that a number of fat loss diets, including low-carbohydrate, low-fat and calorie restriction diets lead to improved insulin action as long as sufficient fat is lost.
I have pointed out the reasons why the carbohydrate-insulin-fat hypothesis is not generally considered viable by the scientific community. I feel I have convinced those who are able to be convinced. I can't convince everyone, and that's all right. It's time for me to move on from this topic, and on to more useful things![/QUOTE]
Read more [url=http://wholehealthsource.blogspot.com.au/2011/09/fat-tissue-insulin-sensitivity-and.html]Whole Health Source: Fat Tissue Insulin Sensitivity and Obesity[/url]