Saturated fat

So eating six slices of bread is inflammatory? I can accept that

Sat fat also lowers triglycerides.

Why do they always lump saturated fat with trans fat together? They are as far apart in chemical structure as fats can be?!?

[QUOTE=peril;1082700]So eating six slices of bread is inflammatory? I can accept that[/QUOTE]

Can you accept that a meal containing two and a half times the carbohydrates from wheat and a third of the fat is less inflammatory?

More seriously, the macros were very different between the two meals on all counts - fat (59.2 vs 20.6% of energy), protein (12.6% vs 6.5%) and carb (28.5% vs 72.9%). How can one draw the conclusion that saturated fat was the significant difference? And of course, the results are interpreted in the context of current theory of artherogenesis rather than established fact. Interesting for forming hypotheses but hardly conclusive. For example, what if it is the protein that makes the difference to endothelial activation? Does this mean we should aim for a diet containing less than 12% protein by energy? Perhaps endothelial activation is a necessary adjunct to eating, with artherogenesis only being a problem in specific circumstances, such as a high LDL particle count. For me these studies really can't tell those of us eating for health much as they only indicate areas for further research

The confounders are everywhere. Thats the point. Pizza.....so we have tomato added to one meal but not the other. Fat...sausage makes up a significant portion and if they are actually considering pizza for the other control I'm not so confident in them choosing pasture raised and properly processed pork product. Like I said its just such muddied water I dunno what you can glean from it if anything. This could be a stuy damning PUFA, supporting tomatoes, or anything in between. Hell, I just read peril's comment and yes even the protein could be suspect.

Actually I'm leaning toward the tomato's being the primary effector here. Good evidence of this in other studies.