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Weight loss gut bacterium found

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  • Weight loss gut bacterium found

    The following is being reported on the BBC that I think is interesting

    Bacteria that live in the gut have been used to reverse obesity and Type-2 diabetes in animal studies. Research, published in Proceedings of the National Academy of Sciences, showed that a broth containing a single species of bacteria could dramatically alter the health of obese mice. It is thought to change the gut lining and the way food is absorbed.
    Similar tests now need to be take place in people to see if the same bacteria can be used to shed the pounds
    The human body is teeming with bacteria - the tiny organisms outnumber human cells in the body 10 to one. And there is growing evidence that this collection of bacteria or "microbiome" affects health.
    Studies have shown differences between the types and numbers of bacteria in the guts of lean and obese people
    Meanwhile gastric bypass operations have been shown to change the balance of bacteria in the gut.
    Researchers at the Catholic University of Louvain, in Belgium, worked with a single species of bacteria Akkermansia muciniphila. It normally makes up 3-5% of gut bacteria, but its levels fall in obesity.
    Mice on a high fat diet - which led them to put on two to three times more fat than normal, lean, mice - were fed the bacteria. The mice remained bigger than their lean cousins, but had lost around half of their extra weight despite no other changes to their diet. They also had lower levels of insulin resistance, a key symptom of Type-2 diabetes.
    Prof Patrice Cani, from the Catholic University of Louvain, told the BBC: "Of course it is an improvement, we did not completely reverse the obesity, but it is a very strong decrease in the fat mass.
    It is the first demonstration that there is a direct link between one specific species and improving metabolism."

  • #2
    thats shocking news to hear up i am amazed with change of behaviour in bacterias
    Last edited by AureliaWaterman; 05-21-2013, 12:31 AM.


    • #3
      This sounds more realistic than all the "wonder pills". Eating habits, lifestyle + this = could be perfect.


      • #4
        Complete BS, the bacteria in that study work similar to Orlistat, by not absorbing fat well (along with fat soluble vitamins) you literally crap out the undigested lipids creating flatulence and oily stools.

        This is more dietary fat phobia, that does not go after the excessive grain and sugar components of weight gain.

        Excuse me for my bad typos,
        Sent from my iPhone using Marks Daily Apple Forum mobile app


        • #5
          Wanna lose weight? Just get a tape worm!

          Yay for more snake oil cures!


          • #6
            C'mon, we all know that fat people are just stupid and lazy. Science ain't gonna help that. [/sarcasm]

            Besides, if one aspect of obesity is actually out of our control, how are thin people going to feel superior? We might actually have to do something other than being thin to gain self-respect.
            "Right is right, even if no one is doing it; wrong is wrong, even if everyone is doing it." - St. Augustine


            Who says back fat is a bad thing? Maybe on a hairy guy at the beach, but not on a crab.


            • #7
              Understanding and manipulating gut microbes will save mankind.

              The specific microbe you mentioned was found and has been studied for several years: The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes

              The newest research links this microbe with several common problems associated with neolithic disease: Gut microbe battles obesity

              There is very little anyone can do with this information and it may end up being a dead-end, but it is a step closer to understanding the interactions between gut microbes and human health. Anyone who denies the interplay between gut microbes and human health is severely deluded.

              Cross-talk between Akkermansia muci... [Proc Natl Acad Sci U S A. 2013] - PubMed - NCBI

              We also observed that prebiotic feeding normalized A. muciniphila abundance, which correlated with an improved metabolic profile. In addition, we demonstrated that A. muciniphila treatment reversed high-fat diet-induced metabolic disorders, including fat-mass gain, metabolic endotoxemia, adipose tissue inflammation, and insulin resistance. A. muciniphila administration increased the intestinal levels of endocannabinoids that control inflammation, the gut barrier, and gut peptide secretion.