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Get some fat in them boobies

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  • Get some fat in them boobies

    It would appear that the monounsaturated fat oleic acid, the prominent fat in olive oil (and beef, and macadamias) suppress overexpression of a major gene in the progression of breast cancer and thus the primal diet, high in monounsaturated fat is very protective.

    Oleic acid, the main monounsaturated fatty acid of... [Ann Oncol. 2005] - PubMed result

    These findings demonstrate that OA, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu overexpression, which, in turn, interacts synergistically with anti-Her-2/neu immunotherapy by promoting apoptotic cell death of breast cancer cells with Her-2/neu oncogene amplification. This previously unrecognized property of OA offers a novel molecular mechanism by which individual fatty acids may regulate the malignant behavior of breast cancer cells and therefore be helpful in the design of future epidemiological studies and, eventually, dietary counseling.

    One caveat would be that linoleic acid is carcinogenic so while I'm not about to poo-poo olive oil, especially since it has other benefits, beef and macadamia are the better choices for saving boobies with fat.

    HER2 (erbB-2)-targeted effects of the omega-3 poly... [Clin Transl Oncol. 2006] - PubMed result

    These findings reveal that the omega-3 PUFA ALA suppresses overexpression of HER2 oncogene at the transcriptional level, which, in turn, interacts synergistically with anti-HER2 trastuzumab- based immunotherapy. ii) Our results molecularly support a recent randomized double-blind placebo-controlled clinical trial suggesting that ALA may be a potential dietary alternative or adjunct to currently used drugs in the management of HER2-positive breast carcinomas. iii) Considering our previous findings demonstrating the <<HER2 upregulatory actions>> of the omega-6 PUFA linolenic acid (LA; 18:2n-6) and the <<HER2 down-regulatory actions >> of the omega-3 PUFA docosahexaenoic acid (DHA; 22:6n-3) and of the omega-9 monounsaturated fatty acid oleic acid (OA; 18:1n-9), it is reasonable to suggest that a low omega-6/omega-3 PUFA ratio and elevated MUFA levels, the two prominent <<fat features>> of the <<Mediterranean diet>>, should be extremely efficient at blocking HER2 expression in breast cancer cells.

    ALA, and especially DHA are down-regulatory on the HER2 gene as well so fish and brains are also great for saving boobies with fat.
    Stabbing conventional wisdom in its face.

    Anyone who wants to talk nutrition should PM me!

  • #2
    Yes, sir. I'm doing my share to save the boobies.

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    • #3
      I eat beef and/ or olive oil on a several time a day basis. My boobies are safe for another night.
      Life is not a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside, thoroughly used up, totally worn out, steak in one hand, chocolate in the other, yelling "Holy F***, What a Ride!"
      My Latest Journal

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      • #4
        I love boobs so much. They are my favourite things in the world. I just had to say that.
        You lousy kids! Get off my savannah!

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        • #5
          Originally posted by Grumpy Caveman View Post
          I love boobs so much. They are my favourite things in the world. I just had to say that.
          No way, a nice pair of brain lobes are way better.

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          • #6
            Originally posted by Grok View Post
            No way, a nice pair of brain lobes are way better.
            Plus, there's nothing as satisfying is how their legs kick when you're motorboatin' the cerebral cortex!!!

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            • #7
              Dammit... I was hoping this was a thread about what to eat to make them bigger.

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              • #8
                Me too, Diana. Me, too.
                You lousy kids! Get off my savannah!

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                • #9
                  Originally posted by Diana Renata View Post
                  Dammit... I was hoping this was a thread about what to eat to make them bigger.
                  Ha! Me too, since I lost weight, these were the first things to go.

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                  • #10
                    ROF, L. Me too!! I've only lost in the boobie department and I thought I was going to be reading about stopping the trend . . .
                    Started Feb 18 2011

                    Tried basic primal and almost everything else in pursuit of IBS control, mood stability, and weight loss.

                    Journalling here

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                    • #11
                      And I thought you were going to post this:

                      https://www.youtube.com/watch?v=K60G...layer_embedded

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                      • #12
                        Originally posted by jspradley View Post
                        Plus, there's nothing as satisfying is how their legs kick when you're motorboatin' the cerebral cortex!!!
                        I love you so much. XD
                        "Trust me, you will soon enter a magical land full of delicious steakflowers, with butterbacons fluttering around over the extremely rompable grass and hillsides."

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                        • #13
                          Originally posted by Diana Renata View Post
                          Dammit... I was hoping this was a thread about what to eat to make them bigger.
                          hahah +1 thats the only reasoni opened it!
                          Get on my Level
                          http://malpaz.wordpress.com/

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                          • #14
                            Originally posted by SunshynLady View Post
                            Ha! Me too, since I lost weight, these were the first things to go.
                            I must be one lucky grok-ette! Mine got BIGGER when I lost weight, I guess my hormones just balanced out...

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                            • #15
                              Oh...the "motorboat". Yes, love me some boobies! Save the Tah Tahs!
                              If you can just get your....mind together....then come on across to me.....
                              James Marshall (Jimi)Hendrix

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