As an example, I was raised in a Baptist church and a good number of them were fat. Now this was during a time when there was no such thing as a fat acceptance movement but I can see them getting onboard with one. However, I can never see them supporting a gay and lesbian rights group.
And before someone jumps in with homosexuality being a sin, look up gluttony.
As to smoking, a lot of cities are restricting smoking in almost anyplace but your own house. Even bars and resturants are not allowed to have smoking sections. There have been cities that tried to pass laws against smoking in your own house if you have children at home.