Announcement

Collapse
No announcement yet.

Hack my Labs!

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Hack my Labs!

    You get my
    - Omega 6:3 Ratio
    - Vit D results
    - Thyroid, lipid, NMR, CBC, urine, kidney, liver, sex hormone panels & sundries
    - Metametrix GI Effects report
    - Diurnal salivary cortisol

    Appreciate any and all help/thoughts/comments/suggestions, on any portion, or the whole thing in context!

    Background: I had what I considered great health till a decade+ of low-fat, high-grain, high-sugar, low-sleep, high-antibiotic use led to extreme sugar addiction, binge eating disorder, and finally, chronic fatigue & bloating, belly fat for the first time ever, no longer able to stave off weight gain, & increasing food intolerances. Low body temp, BP, pulse as long as I can remember (except when at my fattest, but temp was still 96ish).

    Quit processed foods in 2007 & started buying almost everything from traditional farmers; added in organs, ferments, and broth occasionally. Went primal in 2010. Lost .5lb/wk from 185 to 145. Occasional bingeing, too much preoccupation with eating, and couldn't say 100% no to grains or sweets. 6wks of weekend binges led to 10lb gain spring 2011. Started leptin reset in June, kept restarting till the bingeing stopped in October (after increasing to 65g protein BAB). Lost weight here and there. Quit rare grains and occasional dairy on January 1. Eating breakfast outside with no lenses or socks, every morning.

    No history of fertility problems (conceived the second cycle after every baby), trouble producing enough milk (ample supply for literally, and constantly, the last fourteen years), or miscarriage.

    Currently:
    - no desire to snack
    - no desire for lunch
    - must eat around 6 or will start thinking about (mild) sweets
    - sleeping solidly most nights (had developed occasional insomnia in the last few years)
    - almost no cravings, and these are very small and easy to dismiss
    - skin got silky two weeks ago
    - getting warm at night in the last week
    - lost 6lb in last month, bloat + fat - !!
    - body hair (lost when I went primal) came back when I went on the LR, and just left again last week. ?
    - still dreadfully tired every morning, often needing naps, and peak energy is late in the day

    Labs in next post ...
    Last edited by MamaGrok; 01-25-2012, 12:01 PM.
    5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
    Current Weight: 175lb__________________________________Goal: 135lb
    Deadlift: 240lb________________________________________Back Squat: 165lb
    Bench: 130lb__________________________________________Pre ss: 85lb
    ***Winning a 20-year war against binge eating disorder***

  • #2







    I missed highlighting the most recent BUN/Creatinine ratio - it should be red for out of range.

    My questions next post ...
    5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
    Current Weight: 175lb__________________________________Goal: 135lb
    Deadlift: 240lb________________________________________Back Squat: 165lb
    Bench: 130lb__________________________________________Pre ss: 85lb
    ***Winning a 20-year war against binge eating disorder***

    Comment


    • #3
      So far I've learned that
      - sex hormones are low across the board
      - T4 is not converting well to free T3 and is becoming piles of RT3 instead, indicating leptin resistance, and creating a solvable hypothyroidism ... I think
      - cortisol pattern is odd, but mostly right, but levels are mediocre at best
      - even though I've eaten only rare wheat in the last few months, my gut is still having serious problems with it, and sIgA + ANA panels show borderline autoimmune disease. Time to get straight. Since I've dropped all wheat and dairy in the last three weeks, bloating is steadily decreasing for the first time!

      Some of my questions:
      1. What is the difference between the triglyceride reading for NMR and the regular one?
      2. Do I need adaptogens? Which?
      3. What's an optimal homocysteine score?
      4. Am I hypothyroid? Is the best path just to wait for leptin sensitivit to restore proper conversion of T4 to freeT3?
      5. HDL is still very high, but gut is still very leaky - am I right to assume I should avoid nightshades? Is it important to be meticulous (none of my pastured sausage b/c of the cayenne pepper), or just avoid big, obvious things like tomatoes & potatoes & eggplant & bell peppers?
      6. Do I have a renin/aldosterone problem?
      7. Do I have a fatty liver problem?
      8. How did insulin plummet while HbA1c went up?
      9. No sign of problematic inflammation in stool (lactoferrin) or blood (hsCRP, homocysteine...) - how, if my gut is so clearly hating the rare gluten I was eating? (as evidenced by antigliadin sIgA, fat malabsorption, etc.)
      10. For the across-the-board low sex hormones, is the best approach to fix these (which will accelerate the leptin reset) or to be patient and let the LR fix them? If fix them, what is the best approach to that? Help me understand what these very low numbers mean! Could it just be a normal result of just now resuming cycles after two years of lactational amenorrhea?
      11. Are the slightly-off-optimal results in the blood, urine, and iron panels of any concern? BUN/Cr ratio?
      12. Is there an upper limit to "optimal" for B12?
      13. Explicame again why LDL is going up? Something about that hormone cascade ...
      14. Should I buckle down on the omega 3 ratio or just be patient, since I'm probably just on the tail end of recovering from a sky-high ratio?
      15. What is the most likely cause(s) of my chronic fatigue? Hypothyroidism? Mediocre cortisol? Malabsorption?


      My plan:
      - IV glutathione + GAPS for gut
      - continue leptin reset and 100% grain- and dairy-free, consider 100% cayenne-free (lol, already off the other nightshades)
      - continue focusing on organs, ferments, sea veggies, Mg, Se, D3, ACV or HCl
      - try Robb Wolf autoimmune protocol for a month, with GAPS, and then test re-adding eggs & cayenne, very slowly, one at a time

      I'm looking for a local practitioner to help me coordinate my care, which I also hope to work on with Dr. Jack Kruse (neurologist, leptin reset dude), but in the meantime, I want to learn as much as possible and start myself on the right path, as well as find out what questions to ask and know what issues are likely, to make the best use of our time and efforts.
      5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
      Current Weight: 175lb__________________________________Goal: 135lb
      Deadlift: 240lb________________________________________Back Squat: 165lb
      Bench: 130lb__________________________________________Pre ss: 85lb
      ***Winning a 20-year war against binge eating disorder***

      Comment


      • #4
        If you are strict paleo, and losing weight, these labs are mostly meaningless. File them away and retest in every 3-6 months. If you hit a stall, these labs will speak volumes! You need trendable data. Get your leptin in order, via the reset, eat primal for a few months and recheck--you'll see what I mean. Stressing over this lab sheet will do nothing but harm!

        Comment


        • #5
          I know crystals in urin is not a good thing because it can lead to urinary infections and damages the tissue. I have learned this from my veterinarian, my mastiff had this problem.
          I was told to give her Cranberry Extract to get rid of the crystals.

          My mastiffs diet is mostly just muscle meat and whatever fat comes with this meat. It is commercial muscle meat, and the occassional meaty bone. 1x a week she gets liver. I am guessing a diet high in proteins create these crystals. I've read somewhere that drinking bone broth with muscle meat is important but wasn't explained why.
          Since this test I have made great efforts to get her more organ meats, sweetbreads, brain, pancreas, thymus, liver, lung, heart etc...I have not done another urin test on her since. I wanted to let at least 3 months go by. I've also ditched the tap water for her and she now gets geothermal spring water with tons of minerals.

          Comment


          • #6
            Fat maldigestion might have something to do with your bile production?
            Ox-bile is a good supplement. Although I'm not really sure what Fat-maldigestion means....

            My niece was born with a 'genetic' disorder that won't let her body digest certain fatty acid chains (fats) needed for proper growth and body functions. She was given a supplement (lab produced) that she had to take 1x every day for ~ 10 years. She is finally off of them and digests all the fats on her own.

            Comment


            • #7
              i am a dictator, i am ending all labwork, because it is useless obsessing over meaningless numbers.

              Comment


              • #8
                Clostridia spores = botulism
                Here is what I found on hte net:
                Botulism poisoning can occur due to improperly preserved or home-canned, low-acid food that was not processed using correct preservation times and/or pressure.

                Clostridium botulinum - Wikipedia, the free encyclopedia

                Comment


                • #9
                  First off, I would increase your water intake. You need to dilute out the crystals or you could very well end up with kidney stones. Since you have increased your D3 levels quite a bit in the last year you are more at risk. Do you eat or take vitamin K2?

                  The positive ANA could indicate that you have an early autoimmune disease. Do you have any symptoms of lupus or mixed connective tissue disorder?

                  Are you getting any selenium or iodine in your diet to have with thyroid function/conversion of T3-T4? Could you be too low carb for T4 conversion?
                  Using low lectin/nightshade free primal to control autoimmune arthritis. (And lost 50 lbs along the way )

                  http://www.krispin.com/lectin.html

                  Comment


                  • #10
                    Originally posted by Issabeau View Post
                    I know crystals in urin is not a good thing because it can lead to urinary infections and damages the tissue. I have learned this from my veterinarian, my mastiff had this problem.
                    I was told to give her Cranberry Extract to get rid of the crystals.

                    My mastiffs diet is mostly just muscle meat and whatever fat comes with this meat. It is commercial muscle meat, and the occassional meaty bone. 1x a week she gets liver. I am guessing a diet high in proteins create these crystals. I've read somewhere that drinking bone broth with muscle meat is important but wasn't explained why.
                    Since this test I have made great efforts to get her more organ meats, sweetbreads, brain, pancreas, thymus, liver, lung, heart etc...I have not done another urin test on her since. I wanted to let at least 3 months go by. I've also ditched the tap water for her and she now gets geothermal spring water with tons of minerals.
                    No vegetables at all for your dog? Or ground bone? Dogs are omnivores and need more than just meat.
                    Last edited by jammies; 01-25-2012, 04:01 PM.
                    Using low lectin/nightshade free primal to control autoimmune arthritis. (And lost 50 lbs along the way )

                    http://www.krispin.com/lectin.html

                    Comment


                    • #11
                      Originally posted by Issabeau View Post
                      Clostridia spores = botulism
                      Here is what I found on hte net:
                      Botulism poisoning can occur due to improperly preserved or home-canned, low-acid food that was not processed using correct preservation times and/or pressure.

                      Clostridium botulinum - Wikipedia, the free encyclopedia
                      There are lots of clostridia species. I would be more suspicious of C. diff overgrowth - frequently caused by antibiotic use. I would think a very good probiotic would be a good idea.
                      Using low lectin/nightshade free primal to control autoimmune arthritis. (And lost 50 lbs along the way )

                      http://www.krispin.com/lectin.html

                      Comment


                      • #12
                        Originally posted by dado View Post
                        all lab work...is useless obsessing over meaningless numbers.
                        This. We don't know what the numbers should be. We don't know how to precisely manipulate them. We don't know what the cascade effects are when we DO manipulate them.

                        Comment


                        • #13
                          Originally posted by jammies View Post
                          No vegetables at all for your dog? Or ground bone? Dogs are omnivores and need more than just meat.
                          Yep, she gets apple slices, she hates plant stuff in general, wont eat orange, or berries, wont eat nuts.
                          She loves raw goats milk and a whole cow head with horns. She also loves bacon and licks all my dishes clean after i'm done cooking, she always gets left overs. She likes bone broth, too.
                          I make more of an effort now being primal to give her all the nutrition she needs. I've had her on raw since 9 weeks old...but I was still on SAD at the time and didn't know all the details.
                          And she gets raw knuckle bones every other day.

                          Comment


                          • #14
                            Originally posted by dado View Post
                            i am a dictator, i am ending all labwork, because it is useless obsessing over meaningless numbers.


                            Unless, of course, you feel like shit and are using labs as a tool to point you in the direction of what is malfunctioning in your body.
                            Using low lectin/nightshade free primal to control autoimmune arthritis. (And lost 50 lbs along the way )

                            http://www.krispin.com/lectin.html

                            Comment


                            • #15
                              Let me offer a disclaimer: I do not obsess over labs. Just like I don't obsess over the scale. I'm an engineer. I geek over numbers. They cause me no stress at all. Lubbem. I <3 analysis.

                              Originally posted by otzi View Post
                              If you are strict paleo, and losing weight, these labs are mostly meaningless.
                              I'd agree except I'm having trouble getting rid of *all* the bloating, am very interested in knowing whether my extreme sugar addiction likely came from gut dysbiosis, hormonal imbalance, or something wrong with the endorphin receptors or the like, and most importantly, no longer feeling like I'm running on 10% all the time. I've been primal for years and 100% with no variance at all for a month, and still wake up every day feeling like the dead, improve slightly mid-afternoon, and then repeat the next day. It sucks.


                              - I think the crystals thing is b/c 1) I hadn't had any water in about 20hrs, just a freak thing (and I didn't happen to be thirsty, this really almost never happens, and 2) I had an ultrasound a few years ago reveal one kidney full of stones. I've since had two episodes of completely painless, but very red urine, and I suspect that the raw apple cider vinegar I use daily is dissolving the stones. (I know lemon juice is a common treatment for acute kidney stone attacks.) I suspect that the crystals are the dissolved bits, rather than a sign that I'm on my way to stones, but I want to consider all options.
                              I ABSOLUTELY agree with the necessity of organs and broth, and make an effort to have some of both every day, even if just small amounts.


                              Originally posted by Issabeau View Post
                              Clostridia spores = botulism
                              Ah, but mine is Clostridium Sporogenes, and I'm having a darned hard time finding anything about the cause or effects on the net. I'm interested, b/c it's way out of proportion and I have a history of serious antibiotic use + gut symptoms that point to dysbiosis, but I don't know if Clostridium Sp. can have anything to do with any of those.

                              Originally posted by jammies View Post
                              First off, I would increase your water intake. You need to dilute out the crystals or you could very well end up with kidney stones. Since you have increased your D3 levels quite a bit in the last year you are more at risk. Do you eat or take vitamin K2?

                              The positive ANA could indicate that you have an early autoimmune disease. Do you have any symptoms of lupus or mixed connective tissue disorder?

                              Are you getting any selenium or iodine in your diet to have with thyroid function/conversion of T3-T4? Could you be too low carb for T4 conversion?
                              Before needing to chuck dairy, I consumed copious amounts of Kerrygold butter (rich in K2). Now I'm having an ounce of raw goat liver and 1/4tsp fermented cod liver oil daily, plus pastured eggs. I trust this is enough K2, but don't really know.

                              My aunt has lupus, my mother has MCTD, and my sister has RA, but I haven't had any signs of an AID that I know of. No pain anywhere except occasional stomach tenderness. Just chronic bloating and fatigue for the most part. I was quite surprised to see those results and really, those are some of the most valuable of all, b/c they, combined with the antigliadin sIgA, convinced me that I am NOT one of those who can be 80% primal, or even 98%, as I was. It was slowly killing me. Just since I got rid of the 2% last month, I've seen a huge improvement in bloating and nasal congestion (that I never knew I had - suddenly I can sing beautifully in ways I only dreamed of my whole life).

                              Thanks for all your comments! One thing I'm most interested in is figuring out the source of the sugar addiction.
                              5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
                              Current Weight: 175lb__________________________________Goal: 135lb
                              Deadlift: 240lb________________________________________Back Squat: 165lb
                              Bench: 130lb__________________________________________Pre ss: 85lb
                              ***Winning a 20-year war against binge eating disorder***

                              Comment

                              Working...
                              X