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Treating rosacea/skin redness with "rifamaxin". Looks promising.

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  • Treating rosacea/skin redness with "rifamaxin". Looks promising.

    A link has been proposed between rosacea (or inflamed, angry looking skin) and SIBO (Small intestinal bacteria overgrowth).

    From wiki:

    Intestinal flora may play a role in causing the disease. A recent study subjected patients to a hydrogen breath test to detect the occurrence of small intestinal bacterial overgrowth (SIBO). It was found that significantly more patients were hydrogen-positive than controls indicating the presence of intestinal flora overgrowth (47% v. 5%, p<0.001).

    Hydrogen-positive patients were then given a 10-day course of rifaximin, a non-absorbable antibiotic that does not leave the digestive tract and therefore does not enter the circulation or reach the skin. 96% of patients experienced a complete remission of rosacea symptoms that lasted beyond 9 months. These patients were also negative when retested for intestinal flora overgrowth. In the 4% of patients that experienced relapse, it was found that intestinal flora overgrowth had returned. These patients were given a second course of rifaximin which again cleared rosacea symptoms and normalized hydrogen excretion.
    Very interesting. The more I delve into health and diet research in general, the more evidence I see suggesting there's a fundamental link between the gut and health problems.

    A brief overview on the topic (not sure how to embed videos here, if it's possible):

    Last edited by Sabre; 12-14-2013, 11:58 AM.

  • #2
    I should also add this bit; sometimes a different antibiotic is needed, and it's also very effective:

    In another study, it was found that some rosacea patients that tested hydrogen-negative were still positive for intestinal flora overgrowth when using a methane breath test instead. These patients showed little improvement with rifaximin, as found in the previous study, but experienced clearance of rosacea symptoms and normalization of methane excretion following administration of the antibiotic metronidazole, which is effective at targeting methanogens.[17]
    These results suggest that optimal antibiotic therapy may vary between patients and that diverse species of intestinal flora appear to be capable of mediating rosacea symptoms.
    This may also explain the improvement in symptoms experienced by some patients when given a reduced carbohydrate diet.[18] Such a diet would restrict the available substrates for the microorganisms thought to be causative.

    From what I can ascertain (Chris Kresser has made this point I believe), these antibiotics are narrow-spectrum and less likely to cause such negative side effects as the broad spectrums ones like tetracyclines


    • #3
      This is extremely interesting...on a par with the discovery that ulcers are bacteria-originated (H. Pylori).


      • #4
        I would recommend Dermalmd serum for Rosacea I was on one bottle for 15 days twice a day had to drink a full glass of water when taking.
        I had no side effects..I still have the few red marks which will take time to fade but can cover with makeup.


        • #5


          • #6
            Originally posted by Paris Mathis View Post
            I would recommend Dermalmd serum for Rosacea I was on one bottle for 15 days twice a day had to drink a full glass of water when taking.
            I had no side effects..I still have the few red marks which will take time to fade but can cover with makeup.
            If it worked for you, great. However, I am very skeptical of anyone who compounds some herbs ("Aloe Vera, yarrow extract, lavender extract, roman chamomile extract, black cumin oil, green tea extract, apple cider vinegar, tea tree oil") that I presume you take orally, and succeeds where Big Pharma has failed. Same company has a "vagina tightening" solution......................

            Rosacea is still pretty mysterious. Mine is, fortunately, limited to my nose. After a lot of experimenting with OTC products, my physician a few years ago agree to prescribe what my research showed might work. (A true medical partner, he understood I wasn't your average dolt.) I am on 50mg Doxycicline once a day and use Benzocline (Benzoil peroxide plus Clindomycin) cream to keep the worst of my rosacea at bay. I use a makeup powder to cover the remaining colors. If I am not on at least the Doxy, I get horrible, red,. painful pustules.

            Very interesting about the OP's Rifamaxin. According toe Wikipedia, it's quite expensive. Under the Rosacea topic, Wikipedia says this: "Small intestinal bacterial overgrowth (SIBO) was demonstrated to have greater prevalence in rosacea patients and treating it with locally acting antibiotics led to rosacea lesion improvement in two studies. Conversely in rosacea patients who were SIBO negative, antibiotic therapy had no effect.[13] The effectiveness of treating SIBO in rosacea patients may suggest that gut bacteria play a role in the pathogenesis of rosacea lesions."

            Go to the SIBO page for what the OP quoted and additional information.


            • #7
              I have used many product for rosacea skin but not worked for me and I can safely say that dermalmd's serum product is really good and comparable.

              I'm happy with this product and will buy again.I' m loving it clears rosacea and pores, gives healthy glow and clears skin completely loved it :-)