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Is Stephan Guyenet suggesting Gary Taubes is wrong re insulin resistance?

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  • #16
    Reading more of Stephan work and I'm not sure i agree with what he says here..

    Stephan Guyenet said: So basically, there are these interconnections between the circuits that regulate body fat levels and regulate the response to rewarding food. That is, food that you find tasty, palatable―in certain ways. Those systems are interconnected and they actually influence one another. So for example, if you’re really, really full and you just had really big meals over the last three days, you’re not going to be very interested in eating more food. Whereas if you hadn’t done that―or let’s say, you didn’t eat anything for three days, you’re going to be very, very interested in eating more food.
    IMO this is not quite right, as obese people can pretty much eat again even after having a really big meal. So even though they are full, they are still wanting to snack/graze more foods soon after.

    Dr.Eades explains why:

    Let’s look back at the non-obese person to explain. A non-obese person eats, uses the energy from the food and stores the rest. During the time between meals and during sleep, the non-obese person draws on the stored fat to provide energy. When the fat cell mass decreases to a certain critical point, the body signals the brain that the fat cells need a refill, so the brain initiates the hunger response. The non-obese person eats, uses some energy for immediate needs, fills the fat cells with the rest, uses the stored energy as needed, and then the cycle repeats.

    It doesn’t work that way in the obese. Obese people eat, use the energy required for immediate needs and store the rest. But–and this is the extremely important ‘but’– during the time between meals and during sleep, obese people can’t access their fat stores because their baseline insulin is too high. When they can’t get to their stored fat, the lack of access to energy sets in motion all the same biochemical signals in the obese person that get sent in the non-obese, who have depleted the energy storage in their fat cells. And these signals are converted by their brains into the drive to feed, i.e., intense hunger. They have to eat to provide for their immediate energy needs because, thanks to chronically elevated insulin levels, they can’t get into to their own stored fat, even though it’s there waiting in massive quantities.

    To use an analogy, it would be like being out of cash when you desperately needed it yet having a huge amount of money in the bank. You hustle to an ATM machine and find your card won’t work. It’s the same with the obese – they have plenty of energy to go without eating for months, but their fat ATM cards don’t work. And since their fat ATM cards don’t work, the only option they have for immediate energy is to eat.

    So fat people are fat not because they overeat – they overeat because they’re fat.


    • #17
      Ignore them both.