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  • Conversion problem (T3)

    I have a problem with conversion of T4 to T3. I have normal TSH and T4, but my t3 is below the range. I also have high LDL and TC.
    I would appreciate any recommendations. My doctor ignored my thyroid results, but recommended statins which I am not inclined to take. I on the other hand would like to fix my thyroid problem. It's possible, however, that I am wrong since my medical knowledge is non-existing. My doctor is good.

  • #2
    Originally posted by anna5 View Post
    I have a problem with conversion of T4 to T3. I have normal TSH and T4, but my t3 is below the range. I also have high LDL and TC.
    I would appreciate any recommendations. My doctor ignored my thyroid results, but recommended statins which I am not inclined to take. I on the other hand would like to fix my thyroid problem. It's possible, however, that I am wrong since my medical knowledge is non-existing. My doctor is good.
    Whats your diet like?

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    • #3
      Originally posted by anna5 View Post
      I have a problem with conversion of T4 to T3. I have normal TSH and T4, but my t3 is below the range. I also have high LDL and TC.
      I would appreciate any recommendations. My doctor ignored my thyroid results, but recommended statins which I am not inclined to take. I on the other hand would like to fix my thyroid problem. It's possible, however, that I am wrong since my medical knowledge is non-existing. My doctor is good.
      You need to find a better doctor ASAP even if it means paying out of pocket. Naturopaths are good for thyroid problems since they look at the whole picture. If that's not an option, get to an endocrinologist.

      What's probably happening is you are making reverse T3. rT3, as it's called, does nothing for you. T3 is needed to convert cholesterol to hormones. Without T3, your cholesterol rises and your hormones tank.

      There is an adrenal connection and some adrenal support may be needed, but don't try this on your own. Find a doc that will help. Fire any doctor who won't test for T3 and rT3 and thyroid antibodies. TSH and T4 are only helpful in diagnosing subclinical hypothyroidism, which is 90% of what they see. You have bigger issues!

      Don't take the statins whatever you do, that only compounds the problems when you get your T3 back to normal.



      read more:
      The Doctors' Medical Library - Wilsons Reverse T3 Dominance Syndrome, Health and Medical Information

      http://www.custommedicine.com.au/thyroid/

      Comment


      • #4
        Originally posted by anna5 View Post
        I have a problem with conversion of T4 to T3. I have normal TSH and T4, but my t3 is below the range. I also have high LDL and TC.
        I would appreciate any recommendations. My doctor ignored my thyroid results, but recommended statins which I am not inclined to take. I on the other hand would like to fix my thyroid problem. It's possible, however, that I am wrong since my medical knowledge is non-existing. My doctor is good.
        What does your diet look like? How is your Vitamin D level? Your ferritin level? How much do you exercise?

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        • #5
          Thank you, Otzi.

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          • #6
            My vitamin D levels is good now. I have no idea what is my ferritin level, but I started to have a problem after my blood donation - the first I ever had. I suspect that my ferritin level dropped. I don't exercise much.

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            • #7
              You will probably need to get put on Cytomel, which is synthetic T3. I can't believe your doctor is ignoring low T3. Do you know the exact number? Is it below the reference range?

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              • #8
                Otzi, it says it's 82 ng/dl. The range is 94-170.

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                • #9
                  My diet ....
                  Pretty normal right now. For the last couple of years, I gradually eliminated vegetable oils, reduced grains, minimized sugar and significantly increased vegetables. I eat meat/chicken/fish and dairy (yogurt and cheeses). It's possible that I overdid with lowering of carbs - I never counted them. After the tests, I looked at my intake and it was low. I used to be a heavy bakery eater, so I never suspected that I could be on the other end. I've increased my intake recently.
                  I am not fully primal. Ah, there is one ketone (1+) in my urine. I never had it before. Whatever the meaning of it is ... I don't know. I also don't know what my T3 was earlier - it was never tested.
                  Last edited by anna5; 12-22-2012, 01:56 PM.

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                  • #10
                    Up sugar.

                    Cortisol inhibits t4 conversion to t3. Adrenaline also inhibits conversion, and raises antagonistic reverse t3. Aside from that, high fat and high protein diets affect your ability to convert to t4 into t3, as well as deficiencies in vitamin a, selenium, zinc, b2, etc

                    Other than that, small grains of synthetic T3 can help.
                    Make America Great Again

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                    • #11
                      Thank you, Derpanix. "Up sugar" sounds like music. I used to be a heavy sugar eater. I am looking at my deficiencies.

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                      • #13
                        Originally posted by anna5 View Post
                        My vitamin D levels is good now. I have no idea what is my ferritin level, but I started to have a problem after my blood donation - the first I ever had. I suspect that my ferritin level dropped. I don't exercise much.
                        You do not mention whether or not you are experiencing symptoms of low thyroid. If you are what are they?

                        I would get ferritin tested. I would also make sure to get 200 mcg selenium/day-my multi-vitamin has 200 mcg.. Both are needed for conversion. You also have not discussed your diet. Too few calories and/or too few carbs may contribute conversion problems.

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                        • #14
                          You are likely hypothyroid. What was your TSH? As you've been advised, you need another doctor since this one obviously doesn't realize that your LDL issue is because of the low T3. [Once I was treated for hypo, my LDL went steadily down for several years--it was all from low thyroid hormones.] Many doctors think that the 'old' lab ranges of up to 5.0 are a 'normal' TSH when anything above 3.0 is considered problematic, and most good thyroid doctors will treat someone with a TSH above 2.0 who also has symptoms. Moreover, good thyroid doctors know that someone can have 'normal' labs with an underfunctioning thyroid.

                          It took me 5 years to get diagnosed because despite escalating symptoms, my primary kept telling me that my thyroid was 'normal.' When I finally got desperate and self-referred to an excellent endo, I discovered that I have Hashimoto's and was seriously hypothyroid, although my lab numbers didn't reflect the severity of my symptoms.

                          A good thyroid doctor will consider all the numbers--and your T3 certainly needs to be addressed. It's the T3 that really controls our metabolism. I know because problems with conversion are characteristic of Hashi's, and several years after my initial diagnosis, my own T3 tanked, and I've been taking Cytomel ever since. It has saved my life!

                          You need a good thyroid doctor--but they are not easy to find--and are not always endos. I have an endo, but my sister (diabetic and hypothyroid) gets excellent care from her internist.

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                          • #15
                            Originally posted by Derpamix View Post
                            Up sugar.

                            Cortisol inhibits t4 conversion to t3. Adrenaline also inhibits conversion, and raises antagonistic reverse t3. Aside from that, high fat and high protein diets affect your ability to convert to t4 into t3, as well as deficiencies in vitamin a, selenium, zinc, b2, etc

                            Other than that, small grains of synthetic T3 can help.
                            That is false. VERY excessive cortisol secretion inhibits the conversion, but it's very unlikely to get to unhealthy cortisol levels through diet alone as long as you're not in anorexia nervosa or extremist veganism.
                            TOO LOW cortisol secretion is actually linked to hypothyroidism and inability to raise T3 levels even with synthetic or natural thyroid meds. It's all about overall metabolic rate, and cortisol isn't as evil as you make it sound, it's a very important part of the raise in metabolic rate, to allow all hormones to be at their optimal levels. Free cortisol needs to be close to top range, as well as Morning fasting cortisol.

                            I have a serious adrenal problem since the beginning of my "puberty" (or lack of it), and we're on our way to discover what it really is. But it seems primary since I have brownish skin like a sun tan. I have low cortisol, and as a result, I have low T3 and can't raise it (Erfa thyroid makes it worse, consumes the residual cortisol, and leave me with worse TSH and Free T3 levels.)

                            Also, your views (which are Danny Roddy's) on serotonin are reversed, ask anyone on an advanced Hormone Replacement Therapy, ask all the prominent doctors in hormone therapies, anti aging medecine and their recent research.
                            Neurotransmitters are important and not destructive, as everything it's excess of them or wrong reactions that cause problems.

                            I'm experiencing it right now.
                            Young self-caring Paleo-eater from France.
                            (So please forgive the strange way I tend to express myself in your beautiful language )

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