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  • Leptin Resistance Thread



    I'm taking the ball Anand suggested and starting a leptin resistance thread. Especially because I have been on what should be a leptin sensitivity increasing diet for the last few days.


    (My father finally died a week ago today, so for a number of weeks before hand I was eating whatever was convenient. Today is my parent's 66th wedding anniversay.)


    I reviewed on line, um, reviews of The Rosedale Diet and Mastering Leptin books. The former tends run about WHAT you eat (cut the saturated fats, increase MUFA's) and the second more about HOW you eat, meaning at least 5 hours between 3 meals a day.


    I've sort of combined the two. Lots of olive oil, some butter and CO, moderate protein, low carb. Mostly, just waiting between meals. I do miss that eatertainment, the flavor fun, but as to hunger, it's not there. And sometimes I'm honest with myself and postpone a meal.


    I'm running 70-75% fats, 100-110 grams of protein (I have about 177 pounds LBM, so that's in line), and 30-ish grams of carbs. I'm eating a lot of salad as a low carb eatertainment, and good veggies, of course.


    The psychologically noticable event is I look at things like the grapes and orange juice which were for my dad and I have zero interest in them. Or the carby foods out everywhere in the nursing home where my mother is. Zip-ola desire.


    I also notice about fifteen minutes after eating a nice, fatty meal that my metabolism is jacked up. And yes, I've lost two pounds.


  • #2
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    OTB, I'm so sorry to hear about your dad. I hope he wasn't in much pain and that he rests in peace.


    Incidentally, I too was just reading up about Leptin after being intrigued by Anand's post and was going to start a Leptin 101 thread. I'm on a 3-week no-fruit, no-sweetener-of-any-kind, no-starch fast (like South Beach's first phase but with higher amount of fat)since the beginning of the year and I've lost 2 lbs - a first for me since I became Primal. I'm also trying to cut out eatertainment as that used to be (still is?) my biggest problem. And because I've told myself that I can't eat certain things, I don't feel tempted when I look at fruit and dark chocolate. I wonder how the absence of these foods is affecting my leptin sensitivity.

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    • #3
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      OTB, I didn't know your father had passed, may he rest in peace.

      I hope you and the rest of your family are holding up okay.


      I'm intrigued and off to find Anand's thread!


      EDIT - I'm having a dunce day, and would appreciate it if someone could kindly post a couple of links to the original thread or another source of info?

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      • #4
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        My condolences also.


        I too have a current "hunger" for information regarding the role of leptin and how to control it.


        Stephan's Whole Health Source blog has a timely discussion on body fat set points and an upcoming follow-up post very likely to include the role of leptin.


        http://wholehealthsource.blogspot.co...-setpoint.html

        “It is a truism that almost any sect, cult, or religion will legislate its creeds into law if it acquires the political power to do so, and will follow it by suppressing opposition, subverting all education to seize early the minds of the young, and by killing, locking up, or driving underground all heretics.”
        —Robert A. Heinlein

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        • #5
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          OTB:


          So sorry for your loss. Just know you have friends everywhere if you want to talk. Do you still have my email address?

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          • #6
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            OTB, I didn't know your father had passed, may he rest in peace.

            I hope you and the rest of your family are holding up okay.


            I'm intrigued and off to find Anand's thread!


            EDIT - I'm having a dunce day, and would appreciate it if someone could kindly post a couple of links to the original thread or another source of info?
            Here 'ya go -

            http://www.marksdailyapple.com/forum...lateau-busting
            “It is a truism that almost any sect, cult, or religion will legislate its creeds into law if it acquires the political power to do so, and will follow it by suppressing opposition, subverting all education to seize early the minds of the young, and by killing, locking up, or driving underground all heretics.”
            —Robert A. Heinlein

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            • #7
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              Thank you!

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              • #8
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                Sorry, OTB. I hope you and your family are well and are taking care of yourselves.

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                • #9
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                  Asturian, I too follow the Whole Health Source Blog. He's the one who clued me into Leptin.


                  It's a fairly new understanding of how the body regulates hunger, in addition to the new discovery of 'brown fat'.


                  OTB, I'm glad to hear that he is finally not feeling further discomfort. I know that it is a weight off of your shoulders.


                  I, like you and Maba, must be more restrictive in my diet in order to get anywhere. Again, I need more fat and further fasting times between meals. I'm good here and there, but sometimes just give in, telling myself that "I deserve it". I really, really, really need to modify (eliminate) that mentality.

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                  • #10
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                    @NM: This is the thread where Anand talks about leptin resistance.


                    http://www.marksdailyapple.com/forum...-Primal-Wisdom

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                    • #11
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                      Kuno, please shoot me a mail again. I know I have your address, but not under "kuno!" pauv youknowwhat paulv.net


                      Thanks for all the good wishes. Dad died peacefully and without pain in his bed and home of fifty years. The hospice CNA and I were there, the rest of the family was gathering to get here, so they arrived ten minutes later.


                      My mother broke an arm in two places three weeks ago and has been in the hospital three times and in a nursing home for the last three weeks. It is she who now needs care, a lot more than my father ever did. At least my brother and sister are picking up a lot of that care, which they didn't do so much during Dad's long decline.


                      So, from the frying pan to the fire....sigh. "LIfe is what happens......" I thought I'd be planning my escape at this time,but noooooooooo.


                      Oh, yeah, leptin. The thing that made a huge difference in me being able to go hours without eating was knowing that I wasn't just trying to postpone to keep calories down, but I HAVE TO in order to reset my insulin and leptin levels.

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                      • #12
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                        OTB my condolences about your father. I am still not completely familiar with all the details of leptin resistance. I think it is crucial for people like me who are prone to binge eating...

                        “Every saint has a past and every sinner has a future.” -Oscar Wilde
                        "The power of accurate observation is commonly called cynicism by those who have not got it." -George Bernard Shaw
                        "The trouble with jogging is that the ice falls out of your glass." -Martin Mull

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                        • #13
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                          All of Stephan's articles on Leptin:


                          http://wholehealthsource.blogspot.co...h/label/leptin

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                          • #14
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                            I'm glad Leptin Resistance is finally being talked about. Unfortunately, since this problem occurs on the cellular level, neither diet, supplements nor exercise can fix or even affect it. And yes indeed, it can and does cause massive thyroid hormone problems, and therefore outlier high total cholesterol numbers as well.


                            To learn about the *science* of leptin, see:

                            http://health.groups.yahoo.com/group/Leptin_Resistance


                            If you apply to join, please mention you heard about us here and don't forget to give your name. We don't accept anonymous members.


                            Lisa

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                            • #15
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                              Condolences to OTB.


                              Re: Leptin resistance. I'm confused, then. Are we trying to say that leptin resistance is the major factor in obesity and/or body composition?


                              I was currently under the working assumption that body composition was controlled "primarily" by insulin and the inversely-related growth hormone. Too much insulin = inability to access fat as fuel, lack of insulin = fat as a fuel is preferred over carb/protein/muscle tissue.


                              It seems, from what little I've read (about 30 minutes worth), that leptin resistance is a direct result of ingesting too much concentrated-fructose (HFCS, for instance). However, in ingesting so much HFCS, you're going to spike your insulin and weight-gain anyway, right?


                              Of course, the true underlying cause (of either situation) is the choice of food in our diet, right?


                              Am I mistaken? Is this a chicken/egg issue?


                              Thoughts?

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