I asked this of Mark in an e-mail years ago and promptly got off track with a huge stressor in our lives that rather derailed my budding efforts at going primal. As stress tends to do, we wound up physically worse off than before, and it's time to get back on the horse.
Since I'm married and we both cook, major dietary changes need to happen both at once or not at all. One of the reasons the primal thing unhappened the first time is my spouse had an extremely valid complaint about the effects- he is a type 1 diabetic and when exercising and eating by the blueprint as I understood it, he became much more prone to precipitous blood sugar crashes, especially at night during the longest stretch between meals. Getting up at three a.m. every other night at so to either eat some refined carbohydrates or face the emergency glucagon kit (which is not fun, or cheap) was obviously not working. He's very, very conscientous- his view is that aiming for an Hb1AC of 7 as type 1s are supposed to is aiming low, and goes for a number falling in the nondiabetic range- and more often than not at the six-month blood checks he has succeeded at this. It's not his attention and control that are the problem.
As we ease further into this, the sugar crashes are starting to come back right alongside the fat loss and disappearance of too-high sugars. He's started eating more grains again in sheer self-defense and I can't really blame him for that since I don't know how to "fix" it.
I see some type 2s around, but has anybody made primal work with type 1? When things are going well he needs little or none at all of the short-time-range acting insulin (humalog) and not very much of the long-range stuff (lantus). But, the crashes. Any suggestions?