Announcement

Collapse
No announcement yet.

Leptin Reset Experiment starts today - Jack Kruse style

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Originally posted by nuttmegs17 View Post
    Right!

    I have tortilla chips once in a blue moon - avoid everything else like the plague

    I wonder if thanksgiving could have done it- did have more nuts than usual, more grains - not a lot but some, and more milk (normaly I dont touch the stuff).

    Could it be that I had a really busy season? Like worse stress that could do something like that to the antibodies?
    Wow! Hard to believe that 2 days of eating non-gluten grains and dairy would have that harsh of a reaction.

    probably didnt' help that i came off of my busy season at the same time so was stressed. i mean, I avoid all grains like the plague but made exception with dairy and grains for thanksgiving (pies, pie crust, gluten free casserole)

    That is quite the bummer as i figured I could treat myself once or twice a year...however if its having this reaction...I wonder how I can figure out what exactly might have caused my antibodies to go haywire. Outside Thanksgiving, i eat only meat, fat, veggies (avoiding nightshades) with occasional chocolate and wine.

    Comment


    • nutmeggs, I'm interested to know what other in-the-thyroid-know folks have to say about your skyrocketing antibodies. IDK squat about thyroid minutiae, but I have a feeling I'll need to in the near future.


      Owl, THANK YOU for posting that the post-leptin RX explains how the RS works. I'm way behind in reading the blogs (have to go very slowly when I'm inbrain-fog and/or low energy states, which seems to be most of the time lately ), but I just glanced through those portions. So glad to read the explanation finally!

      So please correct me if I'm wrong, but I want to summarize what I read to be sure I understand it.

      In biological history, circadian (once a day) & ultradian (several times a day, like sleep cycles & elimination & eating) rhythms are the most primitive way to regulate certain functions like appetite & energy use or storage (fat maintenance, gain, or loss). More biologically simple creatures use amount of food consumed in relation to the sun's rising and setting to determine whether enough food seems to be available, and whether energy should be stored or burned, and whether appetite should be up- or down-regulated.

      We're advanced! (woohoo!) People have a (relatively speaking) new hormone called leptin that is made by the fat cells and tells the leptin receptors at the brain & muscles & liver whether or not there is enough fat for a rainy day, or whether we need to stop moving & eat more to build up the backup supply. It's an upgrade. But like all upgrades, it's a bit less stable than the most basic model, and it can go awry when feeding becomes grossly departed from what is biologically natural for us.

      At that point (and I've forgotten why this happens; will review later - does the onslaught of massive amounts of carbs make insulin tell leptin to tell the brain "MAKE MORE FAT! MAKE MORE FAT!"?), our leptin receptors are being bombarded by leptin and just get tired of it and say SHUT UP ALREADY! and no longer pay any attention to what leptin has to say. So whether the leptin is high or low, it doesn't matter, b/c the receptors are sticking their fingers in their ears and saying La la la la la I can't heeeeeaaaarrrrr you!!!

      BUT - says Dr. Kruse - there is a backup plan. When a newfangled signal like leptin no longer makes sense to the brain, it reverts to using older biological mechanisms for the functions needed. So the body reverts to using circadian & ultradian rhythms to regulate fat storage. That means that *when* you eat how much tells your body how much fat to store. So eating a big ol' breakfast signals your body that plenty of food is available and fat stores do not need to be increased. (Since I forget why there's so much leptin in the first place, I don't quite follow why this tells the brain to start making less of it ... maybe the low carb diet has already down-regulated the amount of leptin produced, but it didn't matter b/c the receptors were still ignoring it. But what is it that now makes them unplug their ears? Maybe just enough time of the combination of low-carb + the signal from the food timing that tells the brain "Food is not in short supply now"?)

      Now you can lose fat. And gain energy. Hurrah!


      Corrections welcome! I'm trying to pull all these bits and pieces to understand what's going on. This makes me realize that my really irregular sleep patterns are REALLY holding me back. I'm getting enough sleep each day by just staying in bed when sleep is interrupted (whether by a child, staying up late, mid-night waking, or waking too dang early not my fault at all), but my breakfast is all. over. the.map, any time from 7:30 to 11am.
      5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
      Current Weight: 175lb__________________________________Goal: 135lb
      Deadlift: 240lb________________________________________Back Squat: 165lb
      Bench: 130lb__________________________________________Pre ss: 85lb
      ***Winning a 20-year war against binge eating disorder***

      Comment


      • Originally posted by nuttmegs17 View Post
        So basically My FT4 went down slightly, my RT3 went down slightly and my antibodies SKYROCKETED. YIKES
        Question for you - when did you start to take the Armour? Has it been fairly recent?

        I have known a few folks over the years that had Graves or Hashi's or both that were on synthetic thyroid replacement. In an attempt to feel better they changed to dessicated thyroid replacement (which contain pork antigens) and for a few, after some months, it was speculated that the antibodies recognized the pork antigens and mounted an attack thus raising their antibody count. When they returned to the synthetic drugs the issue resolved. Just mentioning this in case this may be your problem?

        Comment


        • Originally posted by nuttmegs17 View Post
          Does anyone know what T3 total indicates? I never paid attention before but I noticed it dropped for me by several points.
          rough description but Total T3 is free T3 and `storage`T3, storage indicating the T3 that is not available for use.

          re your antibodies, hashimoto`s waxes and wanes over your lifetime so 1 blood test can show few antibodies and the next can show excessive antibodies. But generally the fact that it is autoimmune means that your body is attacking your thyroid. if you have hashi`s the general end result is that at some point, could be within 2 weeks or could be 3 decades we don`t know as each person is unique, your body will destroy your thyroid gland.

          Comment


          • Originally posted by Vkiernan View Post
            That is why I am "trying" t3 only. Flying blind cuz no one around here get's it. I am only doing what I know to try based on what I've read. Do not tell me not take my thyroid med. It has at minimum gotten rid of most of my "dark" days and my headaches. I have thought about not taking any thyroid med but I am too scared. Can't afford to go back to where I was mentally.
            +1!

            I`ve seen too many people who have been dragged out of depression or have gotten off statins with proper thyroid supplementation
            there is a definite lack of appreciation for how low t3 can cause depression

            Comment


            • Originally posted by Ice View Post
              Question for you - when did you start to take the Armour? Has it been fairly recent?

              I have known a few folks over the years that had Graves or Hashi's or both that were on synthetic thyroid replacement. In an attempt to feel better they changed to dessicated thyroid replacement (which contain pork antigens) and for a few, after some months, it was speculated that the antibodies recognized the pork antigens and mounted an attack thus raising their antibody count. When they returned to the synthetic drugs the issue resolved. Just mentioning this in case this may be your problem?
              Interesting - I sure hope its not the pork. i've never shown any symptons or allergy after eating pork.
              I've never been on anything other than cytomel and armour - never tired synthroid etc

              Originally posted by maile1 View Post
              rough description but Total T3 is free T3 and `storage`T3, storage indicating the T3 that is not available for use.

              re your antibodies, hashimoto`s waxes and wanes over your lifetime so 1 blood test can show few antibodies and the next can show excessive antibodies. But generally the fact that it is autoimmune means that your body is attacking your thyroid. if you have hashi`s the general end result is that at some point, could be within 2 weeks or could be 3 decades we don`t know as each person is unique, your body will destroy your thyroid gland.
              Man, that is depressing. I guess I was hoping to get the antibodies down and even hopefully get it into remission. I had graves in college and that was put in remission so I figured, why can't it happen with hashis? Plus it has gone into remission for some people (rare I know)

              I am going to see my doctor week after next. Curious what he will say or what we should do? Anyone know anything in particular I might suggest? Should he do some allergy testing? If so, what is a reputable allergy test?

              Comment


              • Originally posted by Indianstar View Post
                Also Jan, I started the epsom salt enema as suggested by you since Magnesium Malate is not available in India. Everytime I use it, within ten minutes I need to go to the bathroom. How can it be a mg supplementation tool then since I hardly get any time to absorb it?
                Hello, Indian Star. I was wondering how the epsom salt enema would work, since if you take epsom salts by mouth they are extremely laxative.

                I've been using "magnesium oil", which is magnesium chloride dissolved in water to make a strong brine. You rub it on your skin, and then wash it off later. It is somewhat sticky, and the websites about it say that if people are very lacking in magnesium, they sometimes have trouble with an itching and burning sensation, but they do well if they add more water to it. Then later then can use it in a stronger solution.

                Even bathing in the ocean can help magnesium status, because there's enough magnesium chloride in solution in seawater to absorb through the skin.

                Try Googling "magnesium oil" to find sources. You could also look on the web for "food grade nigari", which Japanese use to make tofu. It's magnesium chloride, and sometimes quite inexpensive.

                Comment


                • Originally posted by MamaGrok View Post
                  nutmeggs, I'm interested to know what other in-the-thyroid-know folks have to say about your skyrocketing antibodies. IDK squat about thyroid minutiae, but I have a feeling I'll need to in the near future.

                  I'm curious too! I have no idea how common fluctuations are with Hashi's. I assume more antibodies = bigger probs I jsut wish I knew what caused it

                  Comment


                  • I've lost 9.5 inches (from bicep, waist, hips and thighs) and 19.6 lbs in the last 13 weeks. Down to 161.4 lbs from 181 lbs. I was 195 3 years ago when I first starting thinking about being healthier. I can skip meals at will and no longer get hypoglycemic. Its the first time I can remember that the way I eat has had a positive impact on my health and the way I feel.

                    Historically,I've been able to eat whatever I want, whenever I want and I never noticed a difference in the way I felt. I always felt pretty good and had good energy. By I was hypoglycemic, I was always hungry and always eating. I could not skip a meal, not even in childhood. I felt great after eating a steak, a salad or a happy meal. I'd never understood how eating certain kinds of food gave someone more energy or affected their mood. My body didn't seem to care.

                    I think my body is predisposed to take abuse more adaptive. This is good for emergencies, but not good for everyday living.

                    I'm 47 and am 5'9" tall. The weight loss is a side benefit. My hormones have been all out of whack (hypogonadism) and I wanted to fix my health as much as possible with diet before anything else. I burn fat now, not carbs, it's very cool!

                    Thanks Doc K!


                    I'm down to a 34" waistline and I'd like to get to 32".

                    Comment


                    • So much good news, love to hear it!

                      nuttmegs, somewhere you were asking about eye circles. Mine are on and off again lately. Sometimes there, sometimese not, with no apparent correlation to how much sleep I got. Right now they're there, and I've been eating great with no recent dairy, yet they're still back. I haven't figured out what makes it comes and go yet.
                      5'4" 39yo mother to five sweeties & married to their AMAZING DaddyGrok
                      Current Weight: 175lb__________________________________Goal: 135lb
                      Deadlift: 240lb________________________________________Back Squat: 165lb
                      Bench: 130lb__________________________________________Pre ss: 85lb
                      ***Winning a 20-year war against binge eating disorder***

                      Comment


                      • Originally posted by Theta
                        Congratulations and VERY WELL DONE, wanderir! Did it take you 13 weeks to reset?
                        It took me about 11 weeks. I fell off the wagon in minor ways a few times, but my big challenge was conditioning my stomach to eat a BAB first thing, it made me quite ill.

                        It wasn't until week 10 that I could eat a BAB first thing. I'd eat smaller breakfasts a bit later to avoid nausea. Luckily I didn't/don't have much wait to loose, if my body wasn't so good at dealing with abuse, I'm sure I'd have been huge.

                        Comment


                        • Originally posted by wanderir View Post
                          It took me about 11 weeks. I fell off the wagon in minor ways a few times, but my big challenge was conditioning my stomach to eat a BAB first thing, it made me quite ill.

                          It wasn't until week 10 that I could eat a BAB first thing. I'd eat smaller breakfasts a bit later to avoid nausea. Luckily I didn't/don't have much wait to loose, if my body wasn't so good at dealing with abuse, I'm sure I'd have been huge.
                          The BAB is the key to the reset. Once you have that down, everything else will fall into place. I think it took 8-9 weeks for the reset to fully kick in for me.
                          Georgette

                          Comment


                          • Originally posted by Vkiernan View Post
                            That is why I am "trying" t3 only. Flying blind cuz no one around here get's it. I am only doing what I know to try based on what I've read. Do not tell me not take my thyroid med. It has at minimum gotten rid of most of my "dark" days and my headaches. I have thought about not taking any thyroid med but I am too scared. Can't afford to go back to where I was mentally.
                            Use only as much as it it helping you. more does not mean better.
                            You really should have decent cortisol levels so you could utilize all that T3.

                            Very quickly you are getting to a point of what you are trying to accomplish,
                            surviving from today til tomorrow
                            or
                            looking for a long term solution.

                            decisions, decisions



                            ..
                            Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

                            Comment


                            • Originally posted by wanderir View Post
                              Historically,I've been able to eat whatever I want, whenever I want and I never noticed a difference in the way I felt. I always felt pretty good and had good energy. By I was hypoglycemic, I was always hungry and always eating. I could not skip a meal, not even in childhood. I felt great after eating a steak, a salad or a happy meal. I'd never understood how eating certain kinds of food gave someone more energy or affected their mood. My body didn't seem to care.
                              Congrats on all the success, Wanderir! I, too, used to have strong hypoglycemic reactions to going a long time without food, but not anymore. Twice this past week I had to fast for medical tests, and by 2:30 PM (20 hour fast) I really felt almost the same as when I had a BAB and small lunch. No moodiness or irritability - just a slight dizziness. I remember being quite surprised by this.

                              Today's lunch was delayed 3 hours - no biggie. But after a normal size portion of ribs and broccoli, I really wanted more. Then I remembered I forgot the Betaine HCl. This happened once before, too, forgot the pills and had increased hunger. I still don't understand this, but it is a good reminder for me.

                              I've got a pain in my right shoulder blade that comes with turning my neck. Really hoping it is not gallbladder related, as I haven't had that issue for many months now. Took some Milk Thistle with my lunch. Pain started before my workout yesterday, so know it is not that. In fact, I'm not sore from my workout (Mark Sisson's Primal Fitness bodyweight) even though I went until I couldn't do any more, except when you push on the muscles in my chest but no problems just moving normally. Can't wait until I can do a real pull-up. My kids are trying, too, in fact - have a hard time getting my turn in.

                              Doc called and said my blood work was in, cut back on my thyroid meds (reduced Armour and omitted Cytomel - has me worried a bit as I have hypo symptoms), and will see him next Sat. to discuss results/hormones.
                              Last edited by DrMommyN; 12-10-2011, 04:22 PM.

                              Comment


                              • My husband and I have been on the Leptin Reset protocol for a couple of months, he fell off the wagon during Thanksgiving. Too many indulgences -- as seen by his Cholesterol levels.

                                Regarding the Vitamin D results -- he has been taking 10,000 units daily.

                                Any input and guidance would be appreciated.

                                Lab Test Result Result Range
                                11/9/2011 12/9/2011
                                VAP
                                Total HDL-C Direct 131 <130
                                Total HDL-C Direct 71 83 >40
                                Total VLDL-C Direct 12 <30
                                Total Cholesterol 178 226 <200
                                Triglycerides 56 35 <150
                                Total APOB100 - Calc 87 <109
                                Total Non-HDL-C (LDL+VLDL) 143 <160
                                LP9a) Cholesterol 14 <10
                                IDL-C 4 <20
                                Real -LDL-C 112 <100
                                Total LDL-C 96 131 <130
                                Remnant Lip (IDL+VLDL3) 12 <30
                                HDL-2 (large Buoyant) 24 >10
                                HDL-3 59 >30
                                VLDL-3 8 <10
                                Cholest/HDL Ratio 2.51 0.0-5.0

                                Magnesium 2.1 1.5-2.5

                                TESTOSTERONE
                                Total Testosterone 314 468 250-1100
                                Testosterone - Free 47.7 35-155

                                SHBG 55 18537.00

                                Pregnenolone 73 13-208

                                Vitamin D, 25-OH 53 60 30-100
                                Vitamin D 25-OH, D3 53 60
                                Vitamin D 25-OH, D2 <4 <4

                                FTI
                                T3 Uptake 36.2 25-35
                                T4 6.6 4.5-12
                                FTI 2.39 1.25-4.55
                                TSH 1.52 0.40-4.50
                                Reverse T3 27 11-32.0
                                Free T4 1.4 0.8-1.8

                                DHEA Sulfate 174 25-240
                                Ferritin 203 20-380

                                CBC
                                Glucose, Fasting 95 78 65-99
                                BUN 19 17 7-25.0
                                Creatinine 0.92 0.83 0.76-1.46
                                Calcium 9.5 9.5 8.6-10.2
                                Total Protein 6.5 6.6 6.2-8.3
                                Albumin 4.7 4.8 3.6-5.1
                                Total Bilirubin 0.7 0.9 0.2-1.2
                                AST (SGOT) 18 18 010-35
                                ALT (SGPT) 23 21 9.0-60
                                Potassium 5 4.2 3.5-5.3

                                Globulin 1.8 2.1-3.7
                                Albumin/Globulin Ratio 2.6 1.0-2.1

                                Comment

                                Working...
                                X