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  • Indianstar journal

    Originally posted by Indianstar View Post
    Dr Kruse AND experts – PLEASE HELP (nobody to help me on Leptin Reset in India)

    Please let me know what supplements to take now. I have given my health background and lab results which came in today.
    • 52 year old woman
    • Menopausal (last period around 2 years back)
    • Was on thyroid medicine for 6 years (Thyronorm is the only available medicine in India). Now off of thyroid medicine for last one year after HCG (supported by regular testing, last test 6 months back. TSH was normal till then)
    • Reverse T3 test is not available in India
    • Was on beta blockers for controlling blood pressure for 2 years (off these medicines for a year now after HCG)
    • Lost 70 pounds through HCG. Gained back 20. Gained another 13 pounds during 6 weeks of reset. At present about 35 pounds overweight.
    • Big belly like that of a pregnant woman
    • Otherwise general good health
    • Completely messed up sleep. Can not sleep for more than 4-5 hours. Sleeping pills do not help either. It has been like this for as long as I can remember
    • Pain in both hip joint areas does not let me fall asleep. Keep on changing posture because can not lie on back or either side. Something like restless leg syndrome but more like restless hips syndrome in my case
    • Got morning and evening Cortisol checked. No salivary test kit available in India.
    • Supplements at present – Multi Vitamin, Melatonin & 5 HTP (not helping at all), multi enzyme
    • Excessive melasma (pigmentation on face)
    • At present gone back to HCG. Eating reset style in terms of timing and no snacking
    • Only available proteins in India are eggs and chicken which is what I eat all the time. Good fish is not readily available in Delhi. Beef and pork not sold in open markets.

    Glucose Fasting 98 mg/dL (70 – 100)
    Glucose PP 102 mg/dL (70 – 140)
    Insulin Fasting (CMIA) 6.6 uIU/mL (2 – 25)
    Insulin PP 53.4 uIU/mL (5-79)
    Cholesterol 181 mg/dL (< 200)
    Triglycerides 133 mg/dL (< 150)
    HDL Cholesterol 78 mg/dL (40 – 60)
    LDL Cholesterol 76.40 mg/dL (< 100)
    VLDL Cholesterol 26.6 mg/dL (< 30)
    Non HDL Cholesterol 103 mg/dL
    CRP (Immunoturbidimetry) 1.3 mg/L (<or 5)
    Ferritin (CLIA) 90.4 ng/mL (10-291)
    Testosterone (CLIA) 41.46 ng/mL (14-76)
    Progesterone (CLIA) 0.10 ng/mL ( Post menopausal 0.1 – 0.2)
    Cortisol Serum Morning (8am) 24.55 ug/dL (4.3 – 22.4)(CLIA)
    Cortisol Evening (5 PM) 9.63 ug/dL (3.09 – 16.66)
    Estradiol E2 (CLIA) 23.04 pg/dL (Post menopausal > 21)
    DHEA –Sulphate (ECLIA) 68 ug/dL (56.2 – 282.9)
    Vitamin D, 25 Hydroxy 12.3 nmol/L

    Free T3 2.20
    Free T4 0.73
    TSH 8.751
    Originally posted by DigitalSurgeon View Post
    Tour PM cortisol is up for sure and this is classic evidence of LR. Remember from my Hormone 101 post......LR leads to IR then to adrenal resistance ......which is an elevated cortisol. This drives up your CRP and lowers your D levels. So since you are limited in India........food wise.....you really need to get a copy of Sisson's or Wolf's book and add a ton of coconut oil to your diet of chicken and eggs. Eat lots of eggs but you really need to supplement some fish oil if your diet is that limited. You can also read my two blogs on supplements......one is for paleo folks and the other is for HCG folks. Your time to reset is going to take longer because you have alot of belly fat, high nighttime cortisol and inflammation present. Just dont give up. I also would push you are to do a primal diet and stay away from HCG this go round.
    I am not a doctor.

    Read:
    Natural Cholesterol Adjustment Theraphy (NCAT))
    Buy books written by dr Dzugan, reference within that link.
    Read and get familiar with approach.
    --------------------
    Usually you do not want to fiddle with thyroid hormones on the beginning, one good reason, you want to adjust everything else and when everything is as it should be, the RT3 would fall into good place.
    Since you can't test for RT3, forget about that noble idea.
    You have (slight) excess of cortisol, that you can use (profitably),
    you have to add thyroid hormones.
    Dr Kruse (rightly) prefers NaturalThyroidHormones.
    They are made of pigs.
    If you have any problem eating pig, I have to tell you that I have seen Jew (Rabin) explaining that this is one of the times when Jews can eat pork.

    You can get Thyroid-S from internet.
    You will need 60-120mg/day or 1-2grains/day
    Online Pharmacy No/Without Prescription,International Overseas Foreign Pharmacy,Internet Pharmacy,Canadian Pharmacy,Mexican Pharmacy,Prescription Drugs,Buy Drugs Online,Buy Medicine Online,Best Online Pharmacy,Cheap Online Pharmacy,Discount Online Ph

    Figure out your dose aiming at
    TSH(1-2)

    Since your TSH is rather high now, you may start with 2 grain on a day #1, test a month latter.
    If you remember your dose of Thyronorm (in mcg) and corresponding TSH, that would help.

    Currently your Total Cortisol is somewhat high in AM and lowish PM.
    More important, indicative, is free cortisol.
    Either measure FreeCortisol, serum
    or
    measure (CBG), Transcortin

    Using thyroid supplementation will use up some of your cortisol and highly likely you will find out yourself with rather good cortisol levels.

    As you get better in other areas, likely you will have to reduce or eliminate thyroid hormones supplementation.

    While we are at thyroid

    buy
    Super Selenium Complex, 200 mcg 100 capsules
    Super Selenium Complex, 200 mcg 100 capsules
    eat 2 pills/day

    after you are on selenium for a month, add

    Lugol's solution
    buy it from
    Thyroid
    use
    one dropperfull/day (put it into your drink)
    after you have finished one vial, continue with
    two dropperfull/week

    If adding Lugol's would make you feel bad, stop it, you may still be low selenium,
    try again 2-4 weeks latter.

    --------------------------------------------------------
    Clarify your cortisol status.
    My lab opens 7AM and last draw I can have 2:30PM, if you have similar situation, follow me.

    do these tests

    Cortisol, Three Specimens (7:30AM, 12PM, 2:30PM)
    Corticosteroid-binding Globulin (CBG), Transcortin

    better, if you have, add this
    Cortisol, Free, Serum (Free Cortisol, Serum Cortisol, CBG)

    --------------------------------------------------------
    Insulin Fasting (CMIA) 6.6 uIU/mL (2 – 25)

    That is very high insulin level.
    You want to have it at less than 2 (hardly detectable)

    I am a male, 71yo, 5'9" 160#
    In 2008 I had fasting insulin worst than you. Insulin=8
    Now it is insulin<2
    Read my story:
    75g Oral Glucose Tolerance & Insulin, plasma

    Shortcut:
    Drop all high and medium GI food.
    GI-glycemic Index
    In food preparation use heat no more than 250F=121C preferably wet heat (steam)

    Get juicer, I have
    Amazon.com: Omega J8005 Nutrition Center Single-Gear Commercial Masticating Juicer, Chrome and Black: Kitchen & Dining

    and coffee grinder

    Your food will consist of
    eggs
    chicken, pork, beef, lamb, fish, any other animal flesh
    gelatin and or stock made with animals, birds and fish bones
    all kinds of edible green vegetable leaves (run thru juicer)
    nothing that grows under ground (too much sugar and or fructose)
    very limited fruits and nuts
    all kind of spices (run thru coffe grinder then mixed with juice)
    ghee, butter, sour cream, lard, beef tails, chicken fat
    cottage cheese
    coconut oil
    red palm oil

    You may want to follow dr Kruise food timing and amounts, ie
    BAS BigAssBreakfast within 30 min of wakeup
    may be lunch
    dinner 4-6hrs before bed time
    no snacking
    lots of green tea

    Note that food timing should improve your sleep problems.
    Board up any windows in your bedroom or (at least) sleep with mask over your eyes and body totally covered (from light).
    You must sleep within about (10PM-7AM) time slot (ie; can't work at night)

    Knox Original Gelatin (32-Count Envelopes), Unflavored, 8-Ounce Boxes (Pack of 2)
    Knox Original Gelatin (32-Count Envelopes), Unflavored, 8-Ounce Boxes (Pack of 2): Amazon.com: Home & Garden
    Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

  • #2
    ==========================
    Desirable
    Vitamin D, 25-Hydroxy---(80-100)ng/mL =(200-250)nmol/L
    Vitamin D, 25-Hydroxy (1 ngmL)=(2.496)nmol/L
    you have
    Vitamin D, 25 Hydroxy 12.3 nmol/L

    Buy
    Amazon.com: Bio-D-Mulsion Forte 1oz - Biotics #1012: Health & Personal Care
    Biotic Research Bio-D-Mulsion Forte, 1drop=2000iu Vit D
    First month
    10drops/day
    then
    5drops/day forever

    While on the sun, take off as much clothes as permissible.
    Exposure to sun, max amount of skin, no suntan lotions or sun-blocks.

    buy
    Super Booster Softgels with Advanced K2 Complex, 60 softgels

    Super Booster Softgels with Advanced K2 Complex
    60 softgels
    Item Catalog Number: 01590

    eat 1/day

    do blood test of

    Vitamin D, 25-Hydroxy
    Osteocalcin, Serum

    to adjust vit D & K(supper booster)
    your sore hips will say thank you.

    Just in case, do

    PTH, serum

    parathyroid hormone (PTH) manages calcium

    ================================================== ==
    (cont next post)



    .
    Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

    Comment


    • #3
      Originally posted by Indianstar View Post
      • 52 year old woman
      • Menopausal (last period around 2 years back)
      • Lost 70 pounds through HCG. Gained back 20. Gained another 13 pounds during 6 weeks of reset. At present about 35 pounds overweight.
      • Big belly like that of a pregnant woman
      • Otherwise general good health
      • Completely messed up sleep.
      Ferritin (CLIA) 90.4 ng/mL (10-291)
      Testosterone (CLIA) 41.46 ng/mL (14-76)
      Progesterone (CLIA) 0.10 ng/mL ( Post menopausal 0.1 – 0.2)
      Cortisol Serum Morning (8am) 24.55 ug/dL (4.3 – 22.4)(CLIA)
      Cortisol Evening (5 PM) 9.63 ug/dL (3.09 – 16.66)
      Estradiol E2 (CLIA) 23.04 pg/dL (Post menopausal > 21)
      DHEA –Sulphate (ECLIA) 68 ug/dL (56.2 – 282.9)
      Vitamin D, 25 Hydroxy 12.3 nmol/L
      Again, I am not a doctor.

      (Always) Be conscious of your posture.
      When standing
      buttocks (glutes) tight
      belly sucked in (yes, the big one)
      shoulders down, slightly ahead
      chin up
      look far ahead, slightly up

      (to place your shoulders properly, when standing up, outstretch your hands, think that you are holding, hugging 4" (1.2 m) beach ball. Keep your shoulders there, while hands are in any position.
      ----------------------------------------------------------------------

      By now you have read all three dr Dzugan's books and his research paper.
      All that cost under $50.

      You are very recent menapausal.
      Watch out when you have a sex.
      -----------------------------------------------------------------------

      Lets talk steroid hormones Panel now.

      Steroid hormones are made from cholesterol that is attached to LDL cholesterol.
      For purpose of this project, it starts with
      pregnenolone
      which is further metabolized with help of enzymes and signals from pituitary (all that can age and do not work as they used)
      and ends in few places
      cortisol
      aldosterone
      5α-Androstane-3α, 17β-Diol Glucuronide, Serum
      Estrone (E1)
      Estradiol (E2)
      Estriol (E3)

      Most of it is shown on diagram below.
      5α-Androstane-3α, 17β-Diol Glucuronide, Serum-----is metabolite of dihydrotestosterone
      More complicated diagram here:
      KEGG PATHWAY: Steroid hormone biosynthesis - Reference pathway



      All starts with pregnenolone
      but if you took blood (of healthy young, desirable person), by weight, all this (major) steroid hormones combined (in the morning),
      there would be 95% of DHEAs
      there would be 4% of cortisol
      and the remaining 1% would be all other

      As you see, it would be a good idea to emphasize this two hormones first when trying to restore your steroid hormone levels.

      Btw, vitamin D is not on this chart but is also considered steroid hormone.

      You want to restore your steroid hormone levels.

      You may have heard of this type of work. Usually discussion starts and ends with progesterone and estradiol(E2) or all three E's. Sometime testosterone is added.

      I am not against that, but have a different preference as far as sequence of events goes.
      In first phase I prefer emphasis on correcting pregnenolone and DHEAs.
      There is an excellent chance that you will see great improvement throughout.
      Many menstruating women would get all relief that they seek.
      Menopausal women have flat lined LH & FSH that will prevent natural progesterone and E2 fluctuations. We will have to work on it latter.

      Correcting hormonal levels is iterative process.
      You work for a goal. Take (usually) pills, month or two latter do blood test, adjust dose per results.

      Since you are menopausal, we will assign a cycle for you. It will be days of month, to make it easier to remember.
      At first we will work on day #1 (or 1-5)(low), then we will work on day 21 (20-25)(high)

      Use this script:

      1 ------- Complete Blood Count (CBC) With Differential
      2 ------- NMR LipoProfileฎ
      3 ------- Pregnenolone
      4 ------- Progesterone
      5 ------- 17α-Hydroxyprogesterone
      6 ------- Cortisol, Three Specimens (7:30AM, 12PM, 2:30PM)
      7 ------- DHEA
      8 ------- DHEAs
      9 ------- Androstenedione by RIA
      10 ------- Testosterone, Free and Total
      11 ------- SHBG
      12 ------- Dihydrotestosterone
      13 ------- 5α-Androstane-3α, 17β-Diol Glucuronide, Serum
      14 ------- Estrone (E1), Estradiol,Sensitive (E2), Estriol (E3)
      15 ------- Thyroid-stimulating Hormone (TSH)
      16 ------- T4, FT4, T3, FT3, RT3
      17 ------- C-Reactive Protein (CRP), High Sensitivity (Cardiac Risk Assessment)
      18 ------- Vitamin D, 25-Hydroxy
      19 ------- Osteocalcin, Serum

      -------------
      It is important to stay with one laboratory and always the same method of measuring hormones.
      Preferably, have printed script, signed by doctor (not hand written).
      Set it once, keep repeating the testing.

      ====================================

      Set your self spreadsheet, keep updating it after new test results are known.
      Of bottom of the script write new protocol.

      See what I am doing for my self, here (I am a men):
      JanSz Labs & Tests - Page 19


      Code:
      								
      -----------------------		Date	Date	Date	Date	Date	Date	Goal
      pregnenolone---------- 	        xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	230 ng/dL
      progesterone-----------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	1.4 ng/mL
      17-OH-progesterone		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      TCortisol, serum 8AM		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(6.2-19.4)ug/dL
      TCortisol, serum11AM		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(2.3-11.9)ug/dL
      TCortisol, serum2:30PM	        xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	
      DHEAs----------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	275-400 μg/dL
      Androstenedione------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(44-186)ng/dL
      TotalTestosterone----		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(350-1030)ng/dL
      SHBG-----------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      FreeT-Vermulen------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      BAT---Quest----------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      DHT------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      5α-Androstane-3α		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx
      Estradiol,Sens  140244  	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(15-25) pg/mL
      Hemoglobin-----------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(15-16.5)
      TSH------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(0.6-2)
      RT3------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(90-350)pg/mL
      Total Chol-------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(180-200)mg/dL
      LDL--------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<130mg/dL
      HDL-------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	>=60mg/dL
      Trig-------------------		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<150mg/dL
      Vitamin D, 25-Hydroxy		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(80-100)ng/mL
      Osteocalcin, Serum		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	3.2-39.6 ng/mL
      (CRP), High Sensitivity		xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<1, low,   Average risk: 1.00-3.00 mg/L
      HgA1c		                xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<5.7%
      Homocysteine		        xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<11.4micromol/L
      Aldosterone	        	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	<or=28 ng/dL
      ACTH		                xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	xxxxxx	(7-50)pg/mL

      Cont on next post.
      Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

      Comment


      • #4
        cont from previous post



        Until next blood test, based on your tests and guess, you can use:

        Nutricology/ Allergy Research Group

        Micronized Lipid Matrix DHEA 25 mg
        DHEA - Buy DHEA Product by Nutricology/ Allergy Research Group at Herbspro

        Micronized Lipid Matrix Pregnenolone 150 mg
        Pregnenolone - Buy Pregnenolone Product by Nutricology/ Allergy Research Group at Herbspro

        7-Ketoฎ DHEA Metabolite 100 mg, 60 vegetarian capsules Item Catalog Number: 01479
        7-Keto DHEA Metabolite, 100 mg, 60 vegetarian capsules

        Note, Nutricology is a special product, there are other with similar names, many do not work.
        Note, HerbsPro.com (for me in USA), gives best prices (for this produsts) when bought in larger quantity (12 bottles).

        Until next blood test (1-5) of any month, use
        DHEA 2pills /day, one morning, next 2-4 hrs latter (but still in the morning), may go up to 5 pills/day
        7-ketoDHEA 1pill/day morning
        pregnenolone 1pill/day (but may try up to 3 pills a day, go back to smaller dose if any adverse reaction)

        -------------------------------------------
        I started and am currently using this DHEA pills
        since my records are build on it, I am hesitant to switch (to probably better (nutricology) product)
        DHEA (Dehydroepiandrosterone)
        100 mg, 60 capsules
        Item Catalog Number: 00883
        DHEA (dehydroepiandrosterone), 100 mg 60 capsules

        If you want this pills, use 3 pills right away, 2 morning, third latter in the morning.
        Note that is a total of 300mg/day

        -------------------------------------------
        Read this. Note that it is based on work of dr Dzugan.

        DHEA Restoration Therapy - Hormone Replacement Therapy, DHEA, 7-Keto - Life Extension Health Concern
        -------------------------------------------

        I will open new thread for you.

        Either here or on the other thread, if you want to contact me, send PM.
        You may send PM also to musclechatroom.

        It is easy to overlook post.

        ----------------------------
        Good luck.
        There is more.
        All depends of your available resources and will to pursue better health.


        ...

        END
        Last edited by JanSz; 11-02-2011, 08:35 AM.
        Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

        Comment


        • #5
          JanSz, I am speechless. Know what ! When I was posting my problems, I ferevently wished for Dr Kruse and you to respond to my post. I was half blessed when he responded almost immediately (good timing of my post) and now I am completely blessed. I was a bit disappointed when you did not respond because I have seen you help many with your extraordinary knowledge of hormones. It is a lot of information which I need to first understand and then internalise. Thank you seems such a superfluous a phrase for all the efforts you have made to help me ..... but yet - THANK YOU.

          I went to an endo with my results. He put me on 25 mg synthetic T4 since that is the only thing available in India. He had not even heard of Armor or Naturethryoid. It is very difficult for me to get any of your recommended products shipped to India because of our customs laws and heavy duty. Vitamin D3 is available here only in powder form. He has prescribed 60,000 IU every week. Except for that, he does not believe I need anything.

          As you may be aware, almost all of healthcare spend in India is out of pocket (only government employees avail free facilities and unfortunately I am not one). I will try to follow as many testing protocols you have recommended as I possibly can.

          I am committed to my health and well-being. Amen !

          Comment


          • #6
            Originally posted by Indianstar View Post
            JanSz, I am speechless. Know what ! When I was posting my problems, I ferevently wished for Dr Kruse and you to respond to my post. I was half blessed when he responded almost immediately (good timing of my post) and now I am completely blessed. I was a bit disappointed when you did not respond because I have seen you help many with your extraordinary knowledge of hormones. It is a lot of information which I need to first understand and then internalise. Thank you seems such a superfluous a phrase for all the efforts you have made to help me ..... but yet - THANK YOU.

            I went to an endo with my results. He put me on 25 mg synthetic T4 since that is the only thing available in India. He had not even heard of Armor or Naturethryoid. It is very difficult for me to get any of your recommended products shipped to India because of our customs laws and heavy duty. Vitamin D3 is available here only in powder form. He has prescribed 60,000 IU every week. Except for that, he does not believe I need anything.

            As you may be aware, almost all of healthcare spend in India is out of pocket (only government employees avail free facilities and unfortunately I am not one). I will try to follow as many testing protocols you have recommended as I possibly can.

            I am committed to my health and well-being. Amen !

            There is 25millions government employees in USA and about 70milions working people all together.
            We (the USA) is going down hill, golden goose is dying.
            We would have much better economy if 20milion goverment emploees were laid off, so they would stop telling working people what to do. Remaining 5 milions would be too much already. Not what our Founding Fathers envisioned.

            Keep checking about what is available for you to purchase over internet.

            If you like what I wrote, try complying with it.

            Good luck.



            ...
            Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

            Comment


            • #7
              Jan, I am also posting at the Indianstar thread separately. Hope you will notice.

              Update –

              I left HCG midway since I stopped losing weight on it.
              I am still 14 pounds above that when I started LR around 10 weeks back
              No improvement in sleep at all.
              Lot of pain in hip joints and neck

              Supplements (you may not begin to imagine how difficult it was for me to find most of them)-

              1. CoQ-10, 30 mg …one a day
              2. Pantothenic Acid, 500 mg….one a day
              3. Vitamin K2 (MK-7), 100 mcg….two a day
              4. Vitamin D3, 60,000 IU….daily for 2 weeks, alternate days for 2 weeks, now 2 in a week
              5. Celenium, 200 mcg…2 a day
              6. Alpha Lipoic Acid, 300 mg…1 a day
              7. Chromium Picolinate, 200 mcg…..2 a day
              8. DHEA, 50 mg…1 a day
              9. Cod liver oil, 300 mg…..2 a day
              10. Microgest (microgenised progesterone), 100 mg….2 a day
              11. Folic Acid, 5 mg….1 a day
              12. Vitamin C…1.5 mg a day
              13. Multi vitamin – 1 a day
              14. Green tea extract tablet, 300 mg…2 a day
              15. Thyronorm (Thyroxine Sodium), 25 mcg…1 a day
              16. Cipralex (escitalopram oxalate) 10 mg…1 a day
              17. Zolfresh, 10 mg (sleeping pill)…1 a day

              Have not started on iodine yet. Still loading with Selenium. The only iodine liquid available here says “Aqueous Iodine Solution I.P. ’66 “. What does it mean? Is it the same as the Lugol that I was advised ?

              Pregnolelone in India is banned. I am planning to buy some from Europe (visiting Paris, Venice and Rome for next 15 days). I have started Progesterone instead. Should I stop?

              Only synthetic T4 is available in India. Online pharmacies demand prescription and no doctor here is aware of pig thyroid. One online store does sell it without prescription but requires me to get it cleared by customs. So only synthetic T4. Should I stop it ?

              Any other advice ?

              Comment


              • #8
                Also Jan, I started the epsom salt enema as suggested by you since Magnesium Malate is not available in India. Everytime I use it, within ten minutes I need to go to the bathroom. How can it be a mg supplementation tool then since I hardly get any time to absorb it?

                Comment


                • #9
                  #12009 page 1201
                  http://www.marksdailyapple.com/forum...tml#post648762
                  --------------
                  Indianstar journal page
                  http://www.marksdailyapple.com/forum...tml#post648765
                  ================================================== =====



                  Originally posted by Indianstar View Post
                  Jan, I am also posting at the Indianstar thread separately. Hope you will notice.

                  Update –

                  I left HCG midway since I stopped losing weight on it.
                  I am still 14 pounds above that when I started LR around 10 weeks back
                  No improvement in sleep at all.
                  Lot of pain in hip joints and neck

                  Supplements (you may not begin to imagine how difficult it was for me to find most of them)-

                  1. CoQ-10, 30 mg …one a day (do blood test to see if it is enough, statins deplete it)
                  2. Pantothenic Acid, 500 mg….one a day
                  3. Vitamin K2 (MK-7), 100 mcg….two a day (it have to be MK-4, Menatetrenone)
                  add vit A (A,D,K2 work in tandem)

                  4. Vitamin D3, 60,000 IU….daily for 2 weeks, alternate days for 2 weeks, now 2 in a week
                  5. Celenium, 200 mcg…2 a day
                  6. Alpha Lipoic Acid, 300 mg…1 a day
                  7. Chromium Picolinate, 200 mcg…..2 a day
                  8. DHEA, 50 mg…1 a day (blood test will tell you your progress
                  9. Cod liver oil, 300 mg…..2 a day
                  10. Microgest (microgenised progesterone), 100 mg….2 a day (do best you can, do blood testing, same time, preg, prog, estradiol, estrone, total estrogens)
                  11. Folic Acid, 5 mg….1 a day
                  12. Vitamin C…1.5 mg a day
                  13. Multi vitamin – 1 a day
                  14. Green tea extract tablet, 300 mg…2 a day
                  15. Thyronorm (Thyroxine Sodium), 25 mcg…1 a day
                  16. Cipralex (escitalopram oxalate) 10 mg…1 a day
                  17. Zolfresh, 10 mg (sleeping pill)…1 a day

                  Have not started on iodine yet. Still loading with Selenium. The only iodine liquid available here says “Aqueous Iodine Solution I.P. ’66 “. What does it mean? Is it the same as the Lugol that I was advised ?

                  Pregnolelone in India is banned. I am planning to buy some from Europe (visiting Paris, Venice and Rome for next 15 days). I have started Progesterone instead. Should I stop?

                  Only synthetic T4 is available in India. Online pharmacies demand prescription and no doctor here is aware of pig thyroid. One online store does sell it without prescription but requires me to get it cleared by customs. So only synthetic T4. Should I stop it ?

                  Any other advice ?
                  ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,.................. ......

                  You are complaining about sleep.
                  --------
                  Cortisol Serum Morning (8am) 24.55 ug/dL (4.3 – 22.4)(CLIA)
                  Cortisol Evening (5 PM) 9.63 ug/dL (3.09 – 16.66)
                  DHEA –Sulphate (ECLIA) 68 ug/dL (56.2 – 282.9)
                  --------

                  Worst of the above is low DHEAs (rather easily correctable (DHEA + 7ketoDhea pills)
                  Assuming that your Cortisol Binding Globulin is average,
                  freeCortisol shape should be similar to your ToatlCortisol(above). Could be better, but is it not bad, specially relative to what other people here show.

                  DHEAs is a major player, in healthy person it is 95% of all major steroid hormones.
                  It is worth the effort to make correction there.

                  You would be better of using pregnenolone
                  instead you are using Microgest (progesterone).

                  On a test, you are low on both, progesterone and estradiol.

                  Progesterone (CLIA) 0.10 ng/mL ( Post menopausal 0.1 – 0.2)
                  Estradiol E2 (CLIA) 23.04 pg/dL (Post menopausal > 21) (I suspect the units may be pg/mL)(I am assuming that your Estradiol E2= 23.04 pg/mL

                  When you are going to laboratory, they assign you to a group of people and that is how they come up with ranges for some hormones.
                  Most important in this discussion are
                  progesterone
                  estradiol
                  DHEAs
                  Testosterone

                  To make it more difficult, test results from one laboratory can rarely be compared to results from other laboratory. Worst, same laboratory, dfferent tests for same item are not comparable.

                  To keep some semblance of order, you must make your business to:
                  ----do blood testing (shy away from saliva, blood spots or any other exotic ways)
                  ----learn ranges for the above four items for a 20-25y old, menstruating women that your particular laboratory is using (since they will not post them on your test report)
                  ----your laboratory may have 2,3,4 tests for each tested item, you have to stick to only one of them, the most sensitive type
                  ----------------------
                  I use LabCorp to do my testing, below is example of ranges:
                  ------------------
                  progesterone
                  Male: 0.2-1.4 ng/mL
                  Female:
                  • Follicular: 0.2-1.5 ng/mL
                  • Ovulation: 0.8-3.0 ng/mL
                  • Luteal: 1.7-27.0 ng/mL
                  • Postmenopausal: 0.1-0.8 ng/mL
                  ------------------
                  Estradiol, Sensitive
                  Male 3-70(pg/mL)
                  Female:
                  Follicular phase 9-175(pg/mL)
                  Periovulatory 107-281(pg/mL)
                  Luteal phase 44-196(pg/mL)
                  Postmenopausal female:
                  Treated 42-289(pg/mL)
                  Untreated 0-19(pg/mL)
                  --------------------

                  Progesterone (CLIA) 0.10 ng/mL ( Post menopausal 0.1 – 0.2)
                  (I am assuming that your Estradiol E2= 23.04 pg/mL
                  ---------------------
                  Possibly latter, with increased DHEAs, your E2 may go up, if not, we will leave it for latter.
                  Your current bigger problem is very low progesterone (creating estrogen dominance)

                  InstaCalc Online Calculator
                  your current P/E molar ratio is 3.8

                  that is very low
                  sources say that it should be 200-300
                  but with anything below 20 you may expect significant discomforts.

                  For your future reference, assuming steady E2= 23.04 pg/mL

                  progesterone=0.1ng/mL---->P/E=3.76
                  progesterone=1ng/mL---->P/E=37.6
                  progesterone=2ng/mL---->P/E=75.19
                  progesterone=3ng/mL---->P/E=112.79
                  progesterone=4ng/mL---->P/E=150.39
                  progesterone=5ng/mL---->P/E=188
                  progesterone=6ng/mL---->P/E=225
                  progesterone=7ng/mL---->P/E=263

                  progesterone=8ng/mL---->P/E=300
                  progesterone=10ng/mL---->P/E=376

                  =============================
                  For healthy young men
                  E2=20pg/mL
                  Progesterone=1.4ng/dL
                  P/E=60.637
                  =============================



                  ...
                  http://forums.realthyroidhelp.com/vi...13378&start=30

                  http://www.yourmenopausetype.com/men.../06112000.html

                  http://new.instacalc.com/421

                  http://www.drlam.com/articles/Estrogen_Dominance.asp

                  According to the late Dr. John Lee, the world's authority on natural hormone therapy, the key to hormonal balance is the modulation of progesterone to estrogen ratio. For optimum health, the progesterone to estrogen ratio should be between 200 and 300 to 1.
                  Last edited by JanSz; 12-16-2011, 10:24 AM.
                  Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

                  Comment


                  • #10
                    #12071

                    http://www.marksdailyapple.com/forum...tml#post650189


                    Originally posted by Indianstar
                    Also Jan, I started the epsom salt enema as suggested by you since Magnesium Malate is not available in India. Everytime I use it, within ten minutes I need to go to the bathroom. How can it be a mg supplementation tool then since I hardly get any time to absorb it?

                    Originally posted by piano-doctor-lady View Post
                    Hello, Indian Star. I was wondering how the epsom salt enema would work, since if you take epsom salts by mouth they are extremely laxative.
                    Good question,
                    and it is not the same, by mouth vs by bottom.
                    I have seen it explained but cant find reference. Have to do with how our signaling works.



                    My Epsom salt enemas come from this place:
                    drmyhill

                    Magnesium Per Rectum - DoctorMyhill

                    After I spend $$ on equipment as described by dr Hill, I had to improce on it,
                    otherwise my laundry bill would skyrocket.
                    Enemas are messy.

                    Originally it was messy but now no drop should be spilled.

                    --------------------------
                    IndianStar

                    When you have the loaded catheter syringe with catheter installed,
                    sit on toilet seat
                    insert catheter 3-4"
                    push piston
                    remove
                    squease anus
                    go and lay down on bed

                    after 2-3 times, it will become routine, any anxiety will fade
                    do this right before bed time
                    lay still in bed
                    if you fall asleep, you may hold the content for couple hours.
                    patience


                    -------------------------------

                    My Green Laser Prostate surgery - Page 8

                    ///////////////////

                    In my description, I have kept original proportions but changed mechanical details.


                    ==============

                    Magnesium Per Rectum
                    From DoctorMyhill
                    Magnesium Per Rectum - DoctorMyhill


                    Giving magnesium by injection is the quickest way of restoring normal blood and tissue levels of magnesium. However, for some patients the injections, whilst giving benefit, are too painful to be considered long term.

                    At a conference in Australia in 1999 I spoke to a doctor who had been trying magnesium sulphate given PR (per rectum - ie up the backside! - like a suppository) with some success. If this technique works, then it would be a cheap, safe, do-it-yourself at home technique which could replace uncomfortable injections. I have now tried magnesium PR with quite a few of my patients and it has been as effective as the injections in some of them.

                    To try this at home, you need some Epsom salts and an enema syringe. Epsom salts are virtually pure magnesium sulphate and are available from chemists. You can buy an enema syringe from the chemist and this can be re-used so long as sensible hygienic precautions are taken between doses.

                    Dissolve 250g of Epsom salts in 1 litre of warm water. This provides 5 grams in 20 ml, equivalent to 600mgs of elemental magnesium. This solution can be stored in the fridge for six months, but do not forget to warm up before use.

                    Small bottles of spring water are 8fl oz=236ml
                    0.236*250g=59g Epsom Salt.

                    1 US cup = 8 oz=236.588237 cc
                    I make my 10 oz coffee using round (measuring) tablespoon of Maxwell House Instant Coffee.
                    Coffee enemas are done with full strenght coffee.
                    For 20cc enema I would need 1 tablespoon coffee.
                    Lets try first half strenght.

                    236ml/20=11.8 portions=11.8/2=6 tablespoons(to get half strenght)
                    I am not giving up to purists who would insist on organic coffee.

                    Wonder if sleeping is going to be affected by "taking" 5oz of full strength coffee in the rear.

                    No, sleep is not disturbed.




                    To load the syringe dip the tip into the magnesium solution, and draw 20ml back into the syringe. Some patients find it easier to hold the magnesium in by starting with a very tiny amount of the liquid and slowly increasing the dose, thus giving the back passage time to get used to the experience! Magnesium is well absorbed through the colon and 600mgs is a good dose. All electrolytes have potential toxicity, so do not use more than 20ml in 24 hours.

                    Insert the tip of the enema syringe into your bottom (perhaps using some KY jelly as a lubricant). Once the tip is in position, slowly squeeze the bulb and the contents will pass into the rectum. It is sensible to lie down for several minutes after! Hold on to the magnesium for as long as possible.

                    If the magnesium is being absorbed, then I would expect patients to get the same response as from a magnesium injection, but of course without the pain. It does work for a useful proportion of CFS patients so is well worth trying if you get benefit from the magnesium injections.

                    ====================
                    Mentor Red Rubber Urethral Catheter - 14 Fr. Price: $1.00
                    http://www.amazon.com/Mentor-Red-Rub...8630522&sr=1-4


                    Catheter Tip 60 CC Syringe Price: $0.72

                    Amazon.com: Catheter Tip 60 CC Syringe: Pet Supplies


                    Fast Weigh M-500 Digital Pocket Scale, 500 by 0.1 G Price: $5.70
                    Amazon.com: Fast Weigh MS-500-BLK Digital Pocket Scale, 500 by 0.1 G: Kitchen & Dining


                    Rite Aid Epsom Salt 64 oz (1.8 kg) Price: $6.99
                    Amazon.com: Rite Aid Epsom Salt 64 oz (1.8 kg): Health & Personal Care

                    ----------
                    Magnesium - treating a deficiency - DoctorMyhill
                    Can you hang on to magnesium?

                    For magnesium to be retained inside cells you need good cell membranes. The two important facets of cell membranes are:
                    Have good antioxidant status - see Antioxidants. (I take them a lots for A1c management and other)
                    Have good levels of fats and Essential Fatty Acids in the diet. See GOOD FATS AND BAD FATS. (I take them)
                    Boron is necessary for normal calcium and magnesium metabolism.

                    I take 3mg of Boron with each Only Trace Minerals pill, I take 3 pills. Total 9mg of Boron
                    Nutritional Supplements - what everybody should be taking all the time even if nothing is wrong - DoctorMyhill
                    Myhill's Magic Minerals would have me use 6*2=12mg of boron
                    ...



                    ...
                    Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

                    Comment


                    • #11
                      http://www.marksdailyapple.com/forum...tml#post687875
                      Indianstar
                      Hi everyone, here I am again to seek your help on a sensitive issue.

                      I have genital herpes since last ten years. Whenever I have consulted the doctors, they have given me some anti viral course for three days and an ointment for local application. They told me that with time the flare ups will become less in number as well as lesser painful.

                      Unfortunately that has not happened. I still get almost 6-8 episodes in a year and they are all terribly painful. By the time I start healing, another flare up is due.

                      Here in India, doctors believe once you have herpes, you have to live with it. My HS CRP is high too.

                      Please guide me on how I can treat this painful condition. If you write any medicine name, please write the main ingredient (medicine compound) instead of brand name since that may not be available in India.

                      I remain in too much pain. I am in terrible pain even as I write this post. Will I have to live with it my whole life ?

                      I have not indulged in sex for last ten years for the same reason. I am a divorced woman of 51 years and have not entered into any relationship because of this humiliating disease.
                      Originally posted by DigitalSurgeon View Post
                      Valtrex is the medicine we use......but keeping your immune system working well will limit your outbreaks.......so eating a paleolithic diet and protecting your gut is the best medicine in my view. When you do get out breaks use Valtrex......you can find information on it on the internet and you can buy it directly on line from many online pharmacies.
                      http://www.marksdailyapple.com/forum...tml#post687883

                      Originally posted by kkcarlton View Post
                      Taking l-lysine can help, too, high dosed at the first sign of an outbreak. Also avoiding foods high in l-arginine like nuts for example.
                      Last edited by JanSz; 01-19-2012, 10:45 AM.
                      Leptin For Dummies http://www.marksdailyapple.com/forum...tml#post595567

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