Your body will adapt to how you train it, so for instance if you train mostly at a large 1RM % then your body will increase in strength. If you want better conditioning as to say for muscular endurance during movements then you need to decrease weight and do more reps. You will find as you do more reps with less weight the burning and fatigue will go away as your body adapts. Sometimes it's not all about explosive strength and power.
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Strength good, conditioning bad. Help.