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I take it you are referring to weight lifting. I would say if you are making gains in muscle mass and or the lbs. you are lifting from week to week/session to session than you are not overworking yourself. The human body can take a tremendous amount of stress before it is "overworked". In fact, a common conception among people is that "you're not working out hard enough unless you become sore". Now I don't agree with this statement, but in the same token if you're not feeling "anything", that's probably not a good indication either.
How's your mood? Are you irritable? Depressed? If so, you are definitely over-taxing yourself.
Also, if you feel sore all the time, have you had your D3 level checked? When I was deficient, I felt like I had DOMS all the time. Descending stairs was very painful. Once I added D3 (now taking 7000 IUs daily) the pain went away.
You also may want to check your thyroid status as well.
Very hard to overtrain the body, but relatively easy to under recover. Keep a workout log, and if you are having consistent decrease in performance and energy levels, scale back and recover. DOMS isn't a tell tale sign to go more or go less, but performance and overall energy levels are usually more reflective of your needs.
A method I use to estimate if I am over training is by checking my heart rate immediately after exercising for 10 seconds ( measure my heart rate for 10 seconds, not exercise for only 10 seconds). Then 50 seconds later check my pulse for another 10 seconds. You have to know what your max/target heart rate is going to be for those 10 seconds, mine is 28 beats in those 10 seconds. Normally my heart rate has dropped by about 5 or 6 beats , to 22 or 23 beats, at the 50 second count. If my heart rate hasn't dropped that amount or is starting to climb, to 26 or 27 beats, then I usually take it easier for a few days, watch my food intake, and do some active recovery such as easy bike rides or yoga.
This seems to work for me and I have avoided over training for the last year since reading about this method off the crossfit endurance website. Hope this helps.