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What I Mean by “Reprogram Your Genes”

Posted By Mark Sisson On February 20, 2010 @ 9:55 am In Gene Expression,Videos | 58 Comments

From time to time I’ll get a comment from a skeptical reader that says something like, “I don’t think it’s possible to reprogram your genes through diet/lifestyle. Of course our genes are set at birth and our DNA, or program, is copied into every cell of our bodies. You cannot modify or reprogram your genetic code.” I’d like to address this misunderstanding.

One of the best ways to illustrate what I mean by “reprogram your genes” is to use the analogy that Duke University’s Randy Jirtle, Ph.D., uses in the following videos. Think of your genome as being like computer hardware. If you were to program your computer you wouldn’t be changing the hardware, rather, you would be changing the software that tells the computer what to do. So just as we talk about reprogramming or programming a computer and don’t suggest that the hardware itself has changed we likewise can talk about reprogramming our genes without suggesting that the genes have changed. In the case of genes what we are really changing is the epigenome. To quote Dr. Jirtle, “the epigenome would be like the software that tells the computer when to work, how to work and how much.”

Luckily for us our genes are not our destiny. We have immense control through lifestyle behaviors to turn some genes on and other genes off for desired physical results. Watch these videos for it to all come together if it hasn’t already.

There are multiple future possible versions of you. It’s up to you to decide which version you will become. It’s up to you to make lifestyle choices that direct genes toward fat burning, muscle building, longevity and wellness, and away from fat storing, muscle wasting, disease and illness.

This is what The Primal Blueprint [7] is all about. It’s why the sub-title of my book is “Reprogram Your Genes for Effortless Weight Loss, Vibrant Health and Boundless Energy”. And it’s what we talk about (either directly or indirectly) day-in and day-out here at Mark’s Daily Apple. We tend to focus on the practical, but epigenetics is at the heart of why we do what we do. Living like Grok [8] just happens to be the best starting point for directing gene expression [9].

So my tip to you today comes straight from the lips of Madonna: Express Yourself.

Hat tip to MDA reader Sam [10] for the videos.



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