It’s the absolute dead of winter, and many of you are subsisting in ruthlessly frigid weather. The local meteorologist cheerfully announces that, since December, you now have 19 more minutes of daylight! Yippee. It’s 4:30, and the sun hasn’t completely sunk below the icy horizon. That’s all the news from Lake Tundra!
As tempting as it is to hibernate in the comfort of our warm living room, the fact remains that, while we’re well within our rights to curse the cold, we need the sunlight.
Yes, in summer, it’s simple. Just get off your duff and walk outside. In January, well, it’s The Christmas Story scene when Ralphie’s mom bundles up his little brother in preparation for the walk to school: “I can’t put my arms down!”
Well, folks, Big Pharma has done it again. This one really takes the cake.
When Merck and Schering-Plough revealed Monday that the active ingredient in their top-selling cholesterol meds Zetia and Vytorin had flunked a clinical trial measuring its effect on artery plaque, they opened themselves up to a barrage of attacks.
This drug doesn’t work. Period. It just doesn’t work,’ said Steven Nissen, head of cardiology at the Cleveland Clinic. U.S. Rep. Bart Stupak, a Michigan Democrat helping to lead a congressional investigation of the study, said, ‘It is easy to conclude that Merck and Schering-Plough intentionally sought to delay the release of this data.
Perhaps you’re stuck in an afternoon meeting after having skipped lunch to finish off a project. You can feel your glucose levels plummeting twenty stories. Your stomach is making noises reminiscent of Sasquatch depictions. Your concentration is quickly waning, and that donut your co-worker is eating across the room suddenly has you locked in and drooling like Pavlov’s dog. (Why does he get to eat now?) You glance at the clock, and it seems like an eternity separates you between the droning lecture of the moment and the chef’s salad waiting in the office frig.
Finally, the excuse you were looking for to hit the bottle: Researchers from Sirtris Pharmaceuticals this week announced that a derivative of an ingredient in red wine may help reverse the signs of aging!
The ingredient in question is resveratol, a naturally occurring substance in wine, that stimulates a gene known as SIRT1. In previous studies, the SIRT1 gene has been found to increase the lifespan of rodents, but this is the first study to test the theory in humans.
There’s been a lively discussion going on in the comment board of yesterday’s “Dear Mark: Pondering Protein” post. I want to make myself clear about what I mean when I say “lean meats”. Here is a markus’s great comment and my reply:
can’t see why you seem to think that Paleolithic man ate lean meats (certainly not on purpose anyway)
many anthropologists and ethnobiologists since the turn of the century noted traditional societies actively sought out the fat – Aborigines come to mind. Never mind the Samburu and Masai herdsmen or the North American Indians or Eskimo (the latter did not all eat fish).
Are you influenced by Cordain?
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