Marks Daily Apple
Serving up health and fitness insights (daily, of course) with a side of irreverence.

Archive for the ‘ Gene Expression ’ Category

30 Dec

Fasting Makes You Active

couchpotatoIt’s a familiar image we might attribute to stereotype: a sluggish, maybe portly individual lying prostrate on the couch, his/her front littered with Dorito crumbs. Could there, however, be truth behind the picture? Is there indeed a connection between incessant snacking and chronic slothdom? Or considered another way, is there a connection between fasting and being active? As a long-time fan of intermittent fasting (and a believer in the research behind it), I’m convinced. A study out this month sheds even more light on the relationship between lethargy and continuous eating.

2 Dec

Environmental Toxins and Gene Expression

toxicIt’s the heart of the Primal Blueprint: understanding that our lifestyle factors direct influence the expression of our genetic code. While the DNA itself is set, the structure fixed, that’s hardly the end of the story – our story. How we live – even where we live – holds significant sway over the final picture. And by picture I mean, of course, the picture of our genes’ activity: when proteins are produced (and how much), when or whether certain genes are turned on or off. This activity, researchers are increasingly finding, is key in the development – or avoidance – of any number of conditions like Parkinson’s, Alzheimer’s and cancer. Rather than a predetermined formula simply set in motion in the womb, our genes demonstrate a much more complex, nuanced interplay. The sum of all our daily choices and exposures direct our epigenetic signaling and the course laid out by that ongoing sequence of gene activity. As I’ve said many a time, our original genetic heritage doesn’t design our physiological fate. How we live determines how our genes play out their hand. No doubt a powerful concept, the comprehension can take us by surprise. The quickly expanding field of epigenetics has, indeed, rewritten old school genetics. It’s even ruffled a few feathers here and there, but isn’t that always the case with new breakthroughs?

6 Aug

Reprogramming Your Genes Starts with Reprogramming Your Mind

thinking of grokReboot, renew, repair, revitalize? What goals went into your decision to join the Primal Challenge this month? (If you’re on the fence, what vision or particular aspirations pull you toward giving it a shot?) What are you looking to change? How do you hope to feel? What would you like to achieve?

Whether you’re ramping up an already Primal style or beginning to “baby-step” it (more on that tomorrow), rest assured that you’re undertaking powerful stuff. As we’ve mentioned in the past, the Primal Blueprint isn’t about quick, temporary fixes or surface level makeovers. (Although you will find yourself feeling slimmer and looking good…) By its very nature, the PB’s reach extends far beyond the number on a bathroom scale, the arch of a flexed muscle, or the fleeting drama of a bikini reveal. For our part, we have bigger things in mind.

1 Jul

The Power of Positive Thinking

positivethinkingAre you realizing the full potential of your mind?

Now, before you recoil in horror from the New Agey guru-lingo that question probably sounded like, bear with me a minute. I was recently thumbing through one of my favorite books, Dr. Bruce Lipton’s The Biology of Belief, and it got me considering the possibility that creative visualization and positive thinking can both play enormous roles in the context of the Primal Blueprint. Lipton’s book discusses the emerging science of gene expression (sound familiar?), including the very PB-friendly notion that our environment – our diet, our stress level, even our state of mind – controls our DNA, rather than the other way around. If that’s the case (and the science seems to be agreeing that it is), our thoughts, actions, and moods might play an even bigger role in our health and general wellness than previously thought.

10 Jan

Forging Your Own Genetic Destiny

iStock 000006110198XSmallAs you may know, at the core of the Primal Blueprint is gene expression – the idea that our genes can be “switched” on or off, or influenced into producing varying amounts of proteins based on environmental factors (like diet, exercise, and exposure to toxins). In fact, the Primal Blueprint is designed around maximizing positive expression and minimizing deleterious gene expression, the idea being that the best way to express our genes is by living like our Primal ancestors. Eating clean, whole foods, getting plenty of exercise, mental stimulation, and sleep – these are the ways Grok lived (if he was lucky), and these are the methods by which our genes are best influenced. And it’s not just conjecture. Time and time again, science (read: unbiased, unaffiliated observations on the human condition) has suggested precisely the same thing about environmental effects on the way our genes work.

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