Marks Daily Apple
Serving up health and fitness insights (daily, of course) with a side of irreverence.

Archive for the ‘ Gene Expression ’ Category

26 Jan

17 Reasons You’re Not Losing Weight

Effective, healthy weight loss isn’t only due to the simplistic calories in, calories out paradigm. Nor is it solely reliant on diet and exercise. It’s everything – it’s all the various signals our body receives from the environment that affect how our genes express themselves and thrive. How we approach the subject matters, too. Our […]

30 Dec

Fasting Makes You Active

It’s a familiar image we might attribute to stereotype: a sluggish, maybe portly individual lying prostrate on the couch, his/her front littered with Dorito crumbs. Could there, however, be truth behind the picture? Is there indeed a connection between incessant snacking and chronic slothdom? Or considered another way, is there a connection between fasting and […]

2 Dec

Environmental Toxins and Gene Expression

It’s the heart of the Primal Blueprint: understanding that our lifestyle factors direct influence the expression of our genetic code. While the DNA itself is set, the structure fixed, that’s hardly the end of the story – our story. How we live – even where we live – holds significant sway over the final picture. […]

6 Aug

Reprogramming Your Genes Starts with Reprogramming Your Mind

Reboot, renew, repair, revitalize? What goals went into your decision to join the Primal Challenge this month? (If you’re on the fence, what vision or particular aspirations pull you toward giving it a shot?) What are you looking to change? How do you hope to feel? What would you like to achieve? Whether you’re ramping […]

1 Jul

The Power of Positive Thinking

Are you realizing the full potential of your mind? Now, before you recoil in horror from the New Agey guru-lingo that question probably sounded like, bear with me a minute. I was recently thumbing through one of my favorite books, Dr. Bruce Lipton’s The Biology of Belief, and it got me considering the possibility that […]

10 Jan

Forging Your Own Genetic Destiny

As you may know, at the core of the Primal Blueprint is gene expression – the idea that our genes can be “switched” on or off, or influenced into producing varying amounts of proteins based on environmental factors (like diet, exercise, and exposure to toxins). In fact, the Primal Blueprint is designed around maximizing positive […]

23 Jul

Relaxation Response

In the last few months we’ve been highlighting new research that illustrates the power of individuals to influence their genetic expression through basic lifestyle choices, whether through diet, exercise, or avoidance of pollution. The message, as always, is that we aren’t passive victims to aging or any propensities in our genetic heritage. How we live […]

22 Jun

Control Your Lifestyle, Control Your Genes

Results of a dramatic study highlighting (guess what) gene expression were published last week by the National Academy of Sciences, and suddenly the popular media is suddenly paying very close attention. The study, which followed 30 men with low risk, early prostate cancer, demonstrates the dramatic role of lifestyle intervention in gene expression and corresponding […]

20 May

Epigenetics and Depression

We just can’t help it. This epigenetics stuff really floats our boat. The last few weeks we’ve brought you a Dear Mark primer on gene expression as well as news on recent studies examining the role of lifestyle/environment on genetic expression. Diabetes, heart disease, even lung function are impacted by external factors like nutrition, exercise, […]

10 May

Metabolic Fingerprinting

Yes, it’s oh-so-middle-school, but we called it! Following the first ever metabolome-wide association study conducted across four countries, researchers are affirming the promise of metabolic fingerprinting in studying the links diet and other lifestyle factors have with specific disease risk. Once again, the focus is on gene expression, the resulting phenotype rather than our initial […]

28 Apr

Dear Mark: Gene Expression

I received tons of emails from last week’s Gene Expression: Location, Location, Location post. Thanks to everybody for their feedback and questions. In the comment section of last week’s post, Ed was interested in other concrete examples of gene expression (the ability of a gene to produce a biologically active protein). In personal emails, others […]

24 Apr

Gene Expression: Location, Location, Location

Geneticists at North Carolina State University have revealed an interesting lesson in gene expression: where you live can have significant impact on how your genes are expressed. The scientists focused on a sample of 46 Moroccan Amazighs, a relatively homogenous group genetically-speaking. The subjects included desert nomads, mountain agrarians and coastal urban residents. The researchers […]

8 Feb

Nature Tops Nurture? Scientists Wrong Again…

They just don’t get it. Maybe they never will. Reader Karen was outraged enough to send us a link to a news story on MSNBC that states “Nature tops nurture for heavy kids, study says. Research on twins finds that weight is 77 percent attributable to genes.” Thanks, Karen. Read the abstract here.

28 Jan

Gotta Love That Genome

Cool news for your Monday – Researchers from Duke University have discovered a way to examine the entire genome and find the “unpackaged” centers that direct gene expression: A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human […]

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